Partial laryngectomy for recurrent glottic carcinoma after radiotherapy

Abstract

If the surgeon is familiar with the different techniques of, and indications for, partial laryngectomy, this can be a good and satisfying treatment in selected patients with radiation failure for glottic cancer

Endoscopic Carbon Dioxide Laser Surgery for Glottic Cancer Recurrence After Radiotherapy

“…10,[23][24][25][26] Our experience of about 35% recurrence after salvage ELS is consistent with the rates published in previous studies. High recurrence rates after ELS are probably the result of understaging of the cancer both before radiotherapy and before ELS, which can lead to undertreatment and positive or close resection margins.…”

“…There are several advantages to using ELS for salvage surgery in recurrent laryngeal cancer compared with open conservative surgery, 10,[22][23][24][25][26] including shortened hospital stay with consequently reduced costs, low complication rate, possibility of avoiding tracheostomy, good functional results (especially in swallowing), and fewer [16][17][18][19][20][21][22] The reported rates for salvage ELS are as follows: local relapses, 6% to 59%; 3-year RFS, 91% to 100%; and preservation of larynx, 50% to 71%. 10,[23][24][25][26] Our experience of about 35% recurrence after salvage ELS is consistent with the rates published in previous studies.…”

Prognostic role of epidermal growth factor-like domain 7 protein expression in laryngeal squamous cell carcinoma

“…1 Despite advances in modern interventions, such as irradiation, endoscopic surgery and open surgery, the five-year survival rate of laryngeal SCC has improved only marginally over the past decades. 2 The recurrence rate is still as high as 45-50 per cent. Following therapy for laryngeal SCC, local recurrence occurs in 5-25 per cent of tumour stage (T) 1 patients, and in 15-50 per cent of T 2 patients (with impaired vocal fold mobility).…”

Supracricoid partial laryngectomies after radiation failure: A multi‐institutional series

“…To avoid total laryngectomy as much as possible, organ-preservation chemoradiation protocols and conservative surgery have been used for primary treatment of laryngeal cancer, reserving total laryngectomy as salvage treatment. [1][2][3] Local recurrence rate after radiation therapy (RT) ranges from 5% to 13% for T1 and from 25% to 30% for T2 laryngeal cancer.4,5 Surgical management of recurrences after RT failure encompasses endoscopic laser excision, 6-8 partial laryngectomies through an open-neck approach, 4,[9][10][11][12][13] and total laryngectomy, which still remains the most widely used procedure in such a scenario. …”