Partial hydatidiform moles have impaired differentiated function (human chorionic gonadotropin and human placental lactogen secretion) in response to epidermal growth factor and 8-bromo-cyclic adenosine monophosphate

Human Chorionic Gonadotropin Secretion and Protein Phosphorylation in Chorionic Tissue.

“…Some of the responses to second messengers seem to occur in a monodirectional manner in certain tissues and in a bidirectional manner in other tissues [1][2][3][4][5]. The hemochorial placenta has a unique mechanism for secreting hormones, and several studies have compared this mechanism with that of other endocrine organs [3][4][5], but many aspects of the regulation of human chorionic gonadotropin (hCG) secretion from Chorionic tissue remain to be clarified [6][7][8][9]. The present study investigated the At the end of each experiment, the culture medium was collected and centrifuged once, and the supernatant thus obtained was stored at -20°C until the assay.…”