Partial Bladder Boost Using Lipiodol Marking During Image-guided Radiotherapy for Bladder Cancer

Abstract

Lipiodol marking is an effective way of demarcating BC. However, it is necessary to address the comorbidities of elderly patients.

Immunotherapy and radiotherapy for older patients with invasive bladder cancer unfit for surgery or chemotherapy: practical proposal by the international geriatric radiotherapy group

“…The contrast agent remains visible during the conventional seven-weeks course of radiotherapy. Many studies have investigated the safety and visibility of Lipiodol on planning CT scan and cone beam CT scan during radiotherapy ( 92 – 95 ). As an illustration, Nakamura et al.…”

“…As an illustration, Nakamura et al. ( 95 ) emphasized the feasibility of partial bladder tumor boost with Lipiodol toward the end of the treatment with IGRT, which decreased the risk of long-term cystitis while allowing long-term local control.…”

Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder

“…As well as the standard CTV, an index tumor CTV has been described which classically encompasses the tumor bed +/À any residual gross tumor with no additional margin for microscopic extension [40,[50][51][52]. This index tumor CTV can be utilized in two situations: partial bladder irradiation (although partial irradiation is not recommended); or when a two dose level approach is considered: either for index tumor dose escalation (with standard dose to the whole bladder) or for whole bladder dose de-escalation (with standard dose to the index tumor).…”