Pars cohort study of non-communicable diseases in Iran: protocol and preliminary results

Gandomkar, Abdullah; Moini, Maryam; Moghadami, Mohsen; Imanieh, Hadi; Fattahi, Mohammad Reza; Ayatollahi, Seyyed Mohammad Taghi; Sagheb, Mohammad Mahdi; Anushiravani, Amir; Mortazavi, Roozbeh; Sepanlou, Sadaf G; Malekzadeh, Reza

doi:10.1007/s00038-016-0848-2

Cited by 41 publications

(53 citation statements)

References 33 publications

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“…Details of the Pars cohort study have already been published 18 . Briefly, it was conducted on 9,264 individuals aged 40–75 years living in Valashahr and neighboring villages (southern Iran).…”

Section: Methodsmentioning

confidence: 99%

Agreement between laboratory-based and non-laboratory-based Framingham risk score in Southern Iran

Rezaei

Seif

Gandomkar

et al. 2021

Sci Rep

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The Framingham 10-year cardiovascular disease risk is measured by laboratory-based and non-laboratory-based models. This study aimed to determine the agreement between these two models in a large population in Southern Iran. In this study, the baseline data of 8138 individuals participated in the Pars cohort study were used. The participants had no history of cardiovascular disease or stroke. For the laboratory-based risk model, scores were determined based on age, sex, current smoking, diabetes, systolic blood pressure (SBP) and treatment status, total cholesterol, and High-Density Lipoprotein. For the non-laboratory-based risk model, scores were determined based on age, sex, current smoking, diabetes, SBP and treatment status, and Body Mass Index. The agreement between these two models was determined by Bland Altman plots for agreement between the scores and kappa statistic for agreement across the risk groups. Bland Altman plots showed that the limits of agreement were reasonable for females < 60 years old (95% CI: −2.27–4.61%), but of concern for those ≥ 60 years old (95% CI: −3.45–9.67%), males < 60 years old (95% CI: −2.05–8.91%), and males ≥ 60 years old (95% CI: −3.01–15.23%). The limits of agreement were wider for males ≥ 60 years old in comparison to other age groups. According to the risk groups, the agreement was better in females than in males, which was moderate for females < 60 years old (kappa = 0.57) and those ≥ 60 years old (kappa = 0.51). The agreement was fair for the males < 60 years old (kappa = 0.39) and slight for those ≥ 60 years old (Kappa = 0.14). The results showed that in overall participants, the agreement between the two risk scores was moderate according to risk grouping. Therefore, our results suggest that the non-laboratory-based risk model can be used in resource-limited settings where individuals cannot afford laboratory tests and extensive laboratories are not available.

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Section: Methodsmentioning

confidence: 99%

Agreement between laboratory-based and non-laboratory-based Framingham risk score in Southern Iran

Rezaei

Seif

Gandomkar

et al. 2021

Sci Rep

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“…Despite substantial advances in major health indicators and socio-economic status in the last two decades, we observe a rise in the prevalence of cirrhosis and chronic liver diseases in Iran. 1,7…”

Section: Introductionmentioning

confidence: 99%

Burden of Liver Diseases: A Review from Iran

Anushiravani

Sepanlou

2019

Middle East J Dig Dis

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There has been an increase in the burden of liver diseases in Iran, with an increasing trend from communicable to non-communicable diseases. Almost 5400 deaths were due to chronic liver diseases in 2017. We aim to provide a concise update on the epidemiological trends of liver diseases in Iran. Estimations of deaths, disability-adjusted life years, prevalence of chronic liver diseases and cirrhosis in Iran with its common etiologies have been reported. We investigated the major causes of chronic liver diseases in Iran, we have reported our hepatology research centers, and also we have depicted the future of liver diseases in Iran. In 2017, there was a rising trend in chronic liver diseases in Iran. The most common etiologies for chronic liver disease were chronic hepatitis B, chronic hepatitis C, and non-alcoholic steatohepatitis with highest mortalities due to liver cancer and hepatitis C. The prevalence of HBV infection has decreased from 2.9% to 1.3% with effective vaccination, but new cases are still seen due to perinatal transmission. Treatment of HCV has dramatically changed with new drugs which are being produced by local pharmaceuticals at a low cost. The main obstacle in its elimination is finding patients and linkage to care. More than a third of our population have non-alcoholic fatty liver disease in which central obesity had a stronger association than weight itself. Iran has a high burden of liver diseases. The Ministry of Health has effectively controlled hepatitis B and is working towards the World Health WHO’s goals for hepatitis C by 2030. This being said, non-alcoholic fatty liver disease is becoming a major threat to our nation’s health and quality of life.

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“…Accordingly, data on age, gender, educational level, ethnicity, province of residence, the population in the area of residence, and the main source of information about COVID-19 were collected. To measure socioeconomic status (SES), we used a short form that was validated for use in Iran to collect data on participants' assets [16]. Level of trust in the healthcare system and perceived fear of COVID-19 were measured using two visual analog scales (VAS), inspired with method had applied by zhao et.…”

Section: Methodsmentioning

confidence: 99%

Public Trust in Healthcare System and Its Correlates during the COVID-19 Epidemic in Iran

Imanieh

Hassani

et al. 2020

Preprint

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Background: Public trust in the healthcare system is a critical necessity of management in public health crises such as the COVID-19 pandemic. To rapidly assess the public trust in the healthcare system during the COVID-19 epidemic and its correlates in Iran.Methods: A cross-sectional rapid assessment was conducted in Iran during the COVID-19 epidemic in the country. A probability proportional to size multistage random sampling was applied. Sampling was done in 15 provinces. We collected data on public perceived fear, public trust in health system and socio-demographics. Ordinary least square regression modeling was applied to identify correlates of public trust.Results: A total of 5250 adults (response rate: 76%) were participated in the study. Mean of reported trust scores was 50.3±22.8, and of fear scores was 72.0±17.8. Being male (p=0.006), higher levels of education (p<0.001) and socio-economic status (p<0.001), and higher fear scores (p<0.001) were independently correlated with trust in healthcare system. Conclusion: At the time of the COVID-19 epidemic in Iran, public trust in healthcare system is low. A dynamic public epidemic communication with appropriate strategies to communicate with higher social classes is urgent in Iran. Rapid assessments to identify appropriate strategies are needed. These results might be generalizable to the other similar countries during the COVID-19 pandemic.

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Pars cohort study of non-communicable diseases in Iran: protocol and preliminary results

Abstract: PCS with its large scale and wealth of socio-economic and medical data can be a unique platform for studying the etiology of non-communicable diseases and effective interventions in Iran.

Cited by 41 publications

References 33 publications

Agreement between laboratory-based and non-laboratory-based Framingham risk score in Southern Iran

Agreement between laboratory-based and non-laboratory-based Framingham risk score in Southern Iran

Burden of Liver Diseases: A Review from Iran

Public Trust in Healthcare System and Its Correlates during the COVID-19 Epidemic in Iran

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