Parry-Romberg Syndrome: a Rare Case Report

Abstract

REFERENCESBackgroundThe purpose of this report is to present a rare entity of Parry-Romberg syndrome. This poorly understood degenerative condition is characterised by atrophic changes affecting one side of the face. The cause of these changes remains obscure.MethodsThe authors report one rare case of a 31 year old female patient with Parry-Romberg syndrome, accompanied by a brief review of literature.ResultsClinical examination of the patient revealed evident facial asymmetry, malar hypoplasia, atrophy of skin and other tissues on the left side, hyperpigmentation of skin on the left side of the face. Final diagnosis of a Parry-Romberg syndrome (“progressive hemifacial atrophy”) was based on thorough clinical and a radiological examination. Treatment using alloplastic implants to improve facial disfigurement was suggested to the patient.ConclusionsIn most cases, Parry-Romberg syndrome appears to occur randomly for unknown reasons. The pathophysiology of the syndrome remains unknown. There is no definitive treatment for this condition but an attempt to use restorative plastic surgery which includes fat or silicone implants, flap/pedicle grafts, or bone implants can be done to improve facial disfigurement.

Three-dimensional imaging of progressive facial hemiatrophy (Parry-Romberg syndrome) with unusual conjunctival findings

“…It is characterized by a slow and progressive unilateral atrophy of the facial tissues including muscles, bones, and skin 1. The extension of atrophy is frequently limited to one side of the face, and the ipsilateral involvement of the body is rare (20% of cases were described as being bilateral) 2. In the present case, there was involvement of only one side of the face.…”

“…It is a rare, acquired, neurocutaneous syndrome of unknown aetiology accounting 1 in 700,000 individuals 2. This condition was first reported by an English physician, Caleb Parry, in 1815, and subsequently elaborated in 1846 by Moritz Romberg 2.…”

“…It is a rare, acquired, neurocutaneous syndrome of unknown aetiology accounting 1 in 700,000 individuals 2. This condition was first reported by an English physician, Caleb Parry, in 1815, and subsequently elaborated in 1846 by Moritz Romberg 2. This syndrome occurs more in women and is frequently limited to one side of the face and cranium; however it may occasionally spread to the neck and one side of the body 3.…”

Parry-Romberg syndrome and morphoea en coup de sabre

“…PRS is a rare progressive but self-limiting degenerative disorder characterised by atrophy of the skin and subcutaneous tissue, and occasionally muscles, cartilage and bone, mainly of one half of the face 1. ECDS is a variant of linear morphoea that typically presents as a unilateral, sclerotic plaque with variable associated localised atrophy on the forehead and frontal scalp 2.…”

Parry-Romberg syndrome in a pediatric patient. A case report.

“…Regarding the dental aspects, the teeth on the affected side are smaller and have shorter roots 7,12,13 .…”