Progressive hemifacial atrophy, also known as Parry-Romberg syndrome, is an uncommon degenerative condition which is poorly defined. It is characterized by a slow and progressive atrophy affecting one side of the face. The onset usually occurs during the first two decades of life. Characteristically, the atrophy progresses slowly for several years, and then it becomes stable. Ophthalmic involvement is common, with progressive enophthalmos which is a frequent finding. Cutaneous pigmentation is common in such conditions, however its extension to the conjunctiva is rarely reported. We report a case of Parry Romberg syndrome with characteristic clinical and radiographic presentation accompanied with rare ocular findings. The clinical features, radiological findings, and differential diagnoses to be considered, and the available treatment options are discussed in this report.
Ossifying fibromas form a part of the spectrum of fibro-osseous lesions of the jaws. They are rare, benign, nonaggressive tumors that are commonly seen in head and neck region. This paper presents the case of a 40-year-old female patient presented with minimal clinical symptoms, diagnosed to be suffering from aggressive form of ossifying fibroma of maxilla involving the maxillary sinus and ethmoid sinus. This paper emphasizes the importance of computed tomography in diagnosing such unapparent aggressive tumors.
This study was undertaken to determine the effect of smoking and diabetes mellitus individually and combined on the total antioxidant capacity (TAC) of saliva in type 2 diabetes mellitus. The study consisted of four groups, one control and three study groups, each with 20 subjects. Salivary and serum samples were collected from all the groups, which were further subjected to biochemical analysis. The observations of the study were subjected to statistical analysis using SPSS software version 12. The level of salivary TAC decreases secondary to diabetes mellitus and smoking. As the duration of diabetes mellitus increases, the level of total antioxidants decreases. Correlation of salivary TAC with Russell's index had a negative correlation. Smoking has a synergistic effect on diabetes mellitus in reducing the salivary total antioxidant level. Further research should be devoted to the possible benefits of supplementation with antioxidant supplements. Saliva is considered to be a representative of serum and salivary analysis is simple and noninvasive. From the clinical standpoint, it may be reasonable to conclude that salivary TAC can be a useful marker to assess the oxidative stress, as an indicator of progression of diabetes mellitus.
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