Parkinson's Disease in Ferrara, Italy, 1967 Through 1987

Granieri, Enrico; Carreras, M; Casetta, Ilaria; Govoni, Vittorio; Tola, Maria Rosaria; Paolino, E.; Monetti, V. C.; Bastiani, P. De

doi:10.1001/archneur.1991.00530200096026

Cited by 73 publications

(69 citation statements)

References 29 publications

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“…Thus, special attention was paid to distinguishing secondary parkinsonism and Parkinson plus syndromes in our study. Epidemiological investigations of PD have often suggested male predominance when comparing the incidence rates in men versus women [5,6,10,11,13]; in other studies, the sexes have been found to be affected almost equally [9,12]. In this study, no significant difference was noted in the age-adjusted annual incidence of PD between the sexes.…”

Section: Discussioncontrasting

confidence: 50%

Incidence of Parkinson’s Disease in Estonia

Taba¹,

Asser²

2003

Neuroepidemiology

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The incidence of Parkinson’s disease (PD) was studied over a 9-year period (1990–1998) in Tartu county, Estonia, with a mean population of 156,417. Based on 264 patients, the average crude incidence rate of PD was 18.8 per 100,000 person-years. The age-adjusted incidence was 16.8/100,000; 18.3 for the urban group and 14.0 for the rural group; 16.6 for men and 17.1 for women. The age-specific incidence was 1.0/100,000 in the age range 30–39 years, reached a maximum of 117.2/100,000 in the age range 70–79 years and declined in the elderly. The incidence of PD was comparable with that found in developed countries, except for a slightly higher (not significant) incidence rate in the urban compared with the rural population in Estonia.

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Section: Discussioncontrasting

confidence: 50%

Incidence of Parkinson’s Disease in Estonia

Taba¹,

Asser²

2003

Neuroepidemiology

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“…In the literature, detailed age-specific prevalence rates were not provided in all publications, and in many cases the reported age range varies. In six studies [21,22,34,35,36,37], the crude prevalence increased steadily with age. D’Alessandro et al [38] and Kis et al [27] reported a peak at the age of 70 (or 75) to 79 years, followed by a reduced prevalence at ages over 80 years, which was similar to the present findings.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological Study and Clinical Profile of Parkinson’s Disease in the Assiut Governorate, Egypt: A Community-Based Study

Khedr

Attar²,

Kandil³

et al. 2012

Neuroepidemiology

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Background: Few comprehensive epidemiological studies of the prevalence of Parkinson’s disease (PD) have been undertaken in Arab countries, and none has been carried out in Egypt. A community-based survey was conducted in the Assiut Governorate to estimate the prevalence and clinical profile of PD. Methods: A community-based study was carried out, with random sampling of 7 districts, involving 6,498 inhabitants. Out of this sample, 578 subjects dropped out, leaving 3,066 males (51.8%) and 2,854 females (48.2%). There were 3,660 urban residents (61.8%) and 2,260 (38.2%) from the rural community. Patients were evaluated using a screening questionnaire, the Unified Parkinson Disease Rating Scale and the Non-Motor Symptoms Scale for PD. Results: Thirty-nine subjects were found to have parkinsonism, giving a crude prevalence rate of 659/100,000 inhabitants. Of these subjects, 33 were diagnosed with PD (21 males), with a mean age of 66.9 ± 8.4 years, a crude prevalence rate of 557/100,000 and an age-specific prevalence rate (≥50 years old) of 2,748/100,000. There were more males than females (3,395 vs. 1,989/100,000), but the difference was not significant. The highest age-specific prevalence rate was recorded among subjects 70–79 years old (7,263/100,000). There was a significantly higher prevalence among rural than urban inhabitants (973 vs. 301/100,000) and among illiterate than literate persons (1,103 vs. 280/100,000). The clinical profile of our patients was similar to that of other populations but was characterized by a high prevalence of mood/cognition dysfunction and gastrointestinal symptoms; there were few reported perceptual problems. Conclusion: The overall prevalence of PD was high, especially in older adults.

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“…A total of 10 of these studies were conducted in Italy [16,17,19,23,24,26,28,29,30,35], followed by 6 studies in the United Kingdom [27,31,32,33,36,38]. Notably, none of the studies were conducted in Germany.…”

Section: Resultsmentioning

confidence: 99%

“…The systematic review comprised 44 studies estimating prevalence or incidence rates of PD of which 21 studies reported age- and gender-specific prevalence as well as the size of the underlying population [14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. To supplement these data by studies that were published after 2004, an additional systematic literature search was performed using the same search strategy as described by von Campenhausen et al [10] (Fig.…”

Section: Methodsmentioning

confidence: 99%

Prevalence, Duration and Severity of Parkinson's Disease in Germany: A Combined Meta-Analysis from Literature Data and Outpatient Samples

Enders¹,

Balzer‐Geldsetzer²,

Riedel³

et al. 2017

Eur Neurol

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Background: Epidemiological data on the prevalence of Parkinson's disease (PD) in Germany are limited. The aims of this study were to estimate the age- and gender-specific prevalence of PD in Germany as well as the severity and illness duration. Summary: A systematic literature search was performed in 5 different databases. European studies were included if they reported age- and gender-specific numbers of prevalence rates of PD. Meta-analytic approaches were applied to derive age- and gender-specific pooled prevalence estimates. Data of 4 German outpatient samples were incorporated to calculate the proportion of patients with PD in Germany grouped by Hoehn and Yahr (HY) stages and disease duration. In the German population, 178,169 cases of PD were estimated (prevalence: 217.22/100,000). The estimated relative illness duration was 40% with less than 5 years, 31% with 5-9 years, and 29% with more than 9 years. The proportions for different HY stages were estimated at 13% (I), 30% (II), 35% (III), 17% (IV), and 4% (V), respectively. Key Message: We provide an up-to-date estimation of age- and gender-specific as well as severity-based prevalence figures for PD in Germany. Further community studies are needed to estimate population-based severity distributions and distributions of non-motor symptoms in PD.

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Parkinson's Disease in Ferrara, Italy, 1967 Through 1987

Cited by 73 publications

References 29 publications

Incidence of Parkinson’s Disease in Estonia

Incidence of Parkinson’s Disease in Estonia

Epidemiological Study and Clinical Profile of Parkinson’s Disease in the Assiut Governorate, Egypt: A Community-Based Study

Prevalence, Duration and Severity of Parkinson's Disease in Germany: A Combined Meta-Analysis from Literature Data and Outpatient Samples

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