We tested biosocial models that posit interactions between biological variables (testosterone, estradiol, pubertal status, and pubertal timing) and social context variables (family, peer, school, and neighborhood) in predicting adolescent involvement with cigarettes and alcohol in a sample of 409 adolescents in grades 6 and 8. Models including the biological and contextual variables and their interactions explained significantly more variance in adolescent cigarette and alcohol involvement than did models including only the main effects of the biological and contextual variables. Post-hoc analyses of significant interactions suggested that, in most case, moderation occurred in the hypothesized direction. Consistent with dual hazards models of adolescent antisocial behaviors, the relationships between the biological and substance use variables became positive and stronger as the context became more harmful. Considerations of adolescent substance use, and perhaps other problem behaviors, should recognize the possible role of biological variables and how their influence may vary by social context.
Keywordshormones; adolescent cigarette use; adolescent alcohol use; biosocial models Research on adolescent problem behaviors has largely been limited to examining the influence of psychological and social factors. However, several theoretical perspectives suggest that biological factors also play a role in the development of adolescent problem behaviors (Flay & Petraitis, 1994;Huba, Wingard, & Bentler, 1980;Jessor, 1991). Collectively, these theories suggest the need to consider biological, psychological, and social factors together to better understand problem behaviors that begin and accelerate during early adolescence. Moreover, they emphasize that individuals are embedded in social contexts and that there is dynamic interaction between the contexts and biological factors. However, most research does not simultaneously consider both contextual and biological variables. In this study, we consider the interaction of biological factors and social contexts as they relate to adolescent involvement with cigarettes and alcohol. The biological variables
NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript to be examined include hormonal processes and characteristics of pubertal development. The social contexts considered include family, peers, school, and neighborhood, which are considered key contexts in the lives of adolescents (Bronfenbrenner, 1979;Brooks-Gunn, 1987). Our hypotheses are guided by dual-hazards models of antisocial behavior which propose that a biological propensity for antisocial behavior will be exacerbated in harmful social contexts.The hormones examined are testosterone for both boys and girls, and estradiol for girls. Testosterone and estradiol are sex steroids from two endocrine groups: androgens (testosterone) and estrogens (estradiol). They are responsible for the sexual maturation changes associated with puberty that typically begin around age 11 for girls and age 12 fo...