Paraoxonase and arylesterase activities in stent restenosis in bare metal stent

Abstract

Our study shows that decreased paraoxonase and arylesterase activities play a significant role in ethiopathogenesis ISR in patients with BMS.

Serum myeloperoxidase/paraoxonase 1 ratio as potential indicator of dysfunctional high-density lipoprotein and risk stratification in coronary artery disease

“…On the other hand, Demirbag et al have recently reported that ISR was negatively correlated with paraoxonase and arylesterase activities in patients with bare-metal stents, suggesting that anti-inflammatory and anti-oxidative effects of PON1 might contribute to alleviation of restenosis[24].Recently, Khera et al have shown that HDL from CAD patients showed less capacity…”

Paraoxonase and Arylesterase Activities in Dipper and Non-Dipper Prehypertensive Subjects

“… 35 Also, Bounafaa et al 36 showed that paraoxonase, arylesterase and HDL-corrected PON1 activities (PON1 activity/HDL ratio) are significantly lower in patients presented with acute coronary syndrome and paraoxonase and arylesterase activities had a significant protective effect even after adjustment for HDL level, age, BMI, and PON1 polymorphism in the logistic regression analyses. Another study by Demirbag et al 37 demonstrated reduced levels of paraoxonase and arylesterase activities in CAD patients who received bare-metal stent and developed in-stent restenosis (IRS) compared to those who did not develop IRS and healthy controls. Besides CAD, both paraoxonase and arylesterase activities were found significantly lower in patients with non-dipper HT than those of dipper hypertensives and healthy subjects.…”