Parainfectious Guillain Barre Syndrome in a Patient Diagnosed with COVID-19

Baştuğ, Aliye; Bektaş, Hesna; Buyuktarakci, Cansu; Bodur, Hürrem

doi:10.21203/rs.3.rs-215097/v1

2021

DOI: 10.21203/rs.3.rs-215097/v1

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Parainfectious Guillain Barre Syndrome in a Patient Diagnosed with COVID-19

Aliye Baştuğ

Hesna Bektaş

Cansu Buyuktarakci

et al.

Abstract: An accumulating evidence suggesting the neurotropic characteristics of the SARS-CoV-2. Although the pathogenesis is unclear, the relationship between COVID-19 and Guillain Barre Syndrome(GBS) has been previously reported. We present a 66-year-old male with para- infectious COVID-19-related GBS admitted with a 2-day bilateral weakness in distal lower limbs. His neurological findings occurred on the third day of the diagnosis of COVID-19. A cerebrospinal fluid examination revealed albumin-cytological dissociatio… Show more

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2021

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Cited by 2 publications

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SARS-CoV-2 Infection and Guillain-Barré Syndrome: A Review on Potential Pathogenic Mechanisms

et al. 2021

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Since December 2019, the world has been facing an outbreak of a new disease called coronavirus disease 2019 (COVID-19). The COVID-19 pandemic is caused by a novel beta-coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 infection mainly affects the respiratory system. Recently, there have been some reports of extra-respiratory symptoms such as neurological manifestations in COVID-19. According to the increasing reports of Guillain-Barré syndrome following COVID-19, we mainly focused on SARS-CoV-2 infection and Guillain-Barré syndrome in this review. We tried to explain the possibility of a relationship between SARS-CoV-2 infection and Guillain-Barré syndrome and potential pathogenic mechanisms based on current and past knowledge.

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SARS-CoV-2 Infection and Guillain-Barré Syndrome: A Review on Potential Pathogenic Mechanisms

et al. 2021

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Guillain-Barré Syndrome in the COVID-19 Pandemic

Tawakul

Al-Doboke

Altayyar

et al. 2021

Neurology International

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There have been several reported cases of severe acute respiratory syndrome (SARS-CoV-2) infection that were associated with an increased incidence of neurological manifestations, including Guillain–Barré syndrome (GBS). This review aims to present information on the reports of GBS associated with coronavirus disease 2019 (COVID-19) infection. Our review is retrospective work examining articles published from the 1 April 2020 to the 8 May 2021 in the English language. We used the diagnostic criteria and classification published by the National Institute of Neurological Disorders and Stroke and Brighton Collaboration. GBS is usually a postinfectious syndrome, but GBS in the COVID-19 pandemic also takes on a para-infectious profile. In the reports, the genetic factor has a role in developing GBS in some patients. In conclusion, the association between COVID-19 and GBS is not very clear. Still, one mechanism is strongly associated with COVID-19 and immune-mediated neurological complications, which is molecular mimicry between SARS-CoV-2 and human autoantigens.

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Parainfectious Guillain Barre Syndrome in a Patient Diagnosed with COVID-19

Cited by 2 publications

References 9 publications

SARS-CoV-2 Infection and Guillain-Barré Syndrome: A Review on Potential Pathogenic Mechanisms

SARS-CoV-2 Infection and Guillain-Barré Syndrome: A Review on Potential Pathogenic Mechanisms

Guillain-Barré Syndrome in the COVID-19 Pandemic

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