Paradigm shift in the effective treatment of caries in schoolchildren at risk

Santos, Valdeci Elias dos; Vasconcelos, Flávia Maria Nassar de; Ribeiro, Andréa Gadelho; Rosenblatt, Aronita

doi:10.1111/j.1875-595x.2011.00088.x

Cited by 87 publications

(140 citation statements)

References 13 publications

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“…This procedure was done whenever we could not retrieve them from the papers and was specially directed to details of the study design to allow judgment of the risk of bias of the included studies. After contacting the authors by e-mail or social networks, 4 of them answered our requests [Yee et al, 2009a;Vasconcelos, 2011;dos Santos et al, 2012a;Seberol and Ökte, 2013]. Among them, 2 sent their thesis for analysis [Vasconcelos, 2011;Seberol and Ökte, 2013].…”

Section: Resultsmentioning

confidence: 99%

“…Additional information about the studies was requested from 6 authors [Chu et al, 2002b;Yee et al, 2009a;Vasconcelos, 2011;dos Santos et al, 2012a;Liu et al, 2012;Seberol and Ökte, 2013]. This procedure was done whenever we could not retrieve them from the papers and was specially directed to details of the study design to allow judgment of the risk of bias of the included studies.…”

Section: Resultsmentioning

confidence: 99%

“…There were 8 studies with samples composed only by primary teeth [Chu et al, 2002a;Yee et al, 2009b;Vasconcelos, 2011;dos Santos et al, 2012a;Zhi et al, 2012;Seberol and Ökte, 2013;dos Santos et al, 2014;Duangthip et al, 2016]; 2 papers used only permanent teeth [Liu et al, 2012;Monse et al, 2012], and 1 study used both teeth [Llodra et al, 2005].…”

Section: Characteristics Of Included Articlesmentioning

confidence: 99%

“…All eligible papers were clinical trials with a parallel design [Chu et al, 2002a;Llodra et al, 2005;Yee et al, 2009b;Vasconcelos, 2011;dos Santos et al, 2012b;Liu et al, 2012;Monse et al, 2012;Zhi et al, 2012;Seberol and Ökte, 2013;dos Santos et al, 2014;Duangthip et al, 2016].…”

Section: Characteristics Of Included Articlesmentioning

confidence: 99%

“…Since its application does not require dental equipment, it can be used outside the clinical environment [dos Santos et al, 2012b]. The product is well accepted even by young children [Chu and Lo, 2008] since it can be applied without caries removal [Chu et al, 2002b].…”

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confidence: 99%

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Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis

Chibinski

Wambier²,

Feltrin³

et al. 2017

Caries Res

145

175

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A systematic review was performed to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in children when compared with active treatments or placebos. A search for randomized clinical trials that evaluate the effectiveness of SDF for caries control in children compared to active treatments or placebos with follow-ups longer than 6 months was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, and grey literature. The risk of bias tool from the Cochrane Collaboration was used for quality assessment of the studies. The quality of the evidence was evaluated using the GRADE approach. Meta-analysis was performed on studies considered at low risk of bias. A total of 5,980 articles were identified. Eleven remained in the qualitative synthesis. Five studies were at “low,” 2 at “unclear,” and 4 studies at “high” risk of bias in the key domains. The studies from which the information could be extracted were included for meta-analysis. The arrestment of caries at 12 months promoted by SDF was 66% higher (95% CI 41-91%; p < 0.00001) than by other active material, but it was 154% higher (95% CI 67-85%; p < 0.00001) than by placebos. Overall, the caries arrestment was 89% higher (95% CI 49-138%; p < 0.00001) than using active materials/placebo. No heterogeneity was detected. The evidence was graded as high quality. The use of SDF is 89% more effective in controlling/arresting caries than other treatments or placebos. The quality of the evidence was graded as high.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Characteristics Of Included Articlesmentioning

confidence: 99%

Section: Characteristics Of Included Articlesmentioning

confidence: 99%

mentioning

confidence: 99%

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Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis

Chibinski

Wambier²,

Feltrin³

et al. 2017

Caries Res

145

175

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The use of silver diamine fluoride in a children's hospital: Critical analysis and action protocol

Brunet‐Llobet

Auría‐Martín

González‐Chópite

et al. 2022

Clinical & Exp Dental Res

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Objectives The present critical analysis aims to propose an action protocol for the use of silver diamine fluoride (SDF) in pediatric patients in a hospital setting, especially for those who are currently awaiting hospital dental treatment under general anesthesia. Material and Methods A literature search was performed in the PubMed/MEDLINE from 2009 to 2021 using the search terms “silver diamine fluoride”, “pediatrics silver diamine fluoride”, “application silver diamine fluoride”, and “AND” ‐ combined with terms: “potassium iodide”, “properties”, “adverse effects”, “early childhood caries”, “patient with disability”, “management”, “special health care needs patient”. Articles that recorded the type of teeth, application protocol, the concentration of the product, and possible complications of the treatment were selected. Results Four hundred and sixteen related articles were obtained, of which 13 were finally chosen on the basis of the search criteria. The age at which the use of SDF was recommended ranged from the first year of life to 12 years, in most cases in primary teeth. The study populations varied in size from 53 to 799 patients. An analysis of the characteristics of SDF and its use in pediatric patients with dental caries was performed. The recommended concentration was 38% SDF, applied twice yearly. The main complication reported was staining. A decision algorithm was designed including SDF as an agent for caries control in patients attending the specific population of our hospital (divided into two groups: healthy children aged 0−4 years and patients with special health care needs (SHCNs) aged 0−18 years). Conclusions SDF therapy appears to be effective in the control of caries in pediatric patients. We propose an action protocol for patients with early childhood caries to reduce risk, complications, and the progression of lesions. The protocol is aimed especially at pediatric patients who also have some systemic pathology, disability, SHCNs, and/or behavioral difficulties.

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The Synergism of Silver and Fluoride: A New Arsenal in Caries Management

Kumar,

2024

Macromolecular Symposia

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Topical anticaries agents are non‐invasive methods to control and prevent dental caries. SDF is a fluoride‐based agent added to the arsenal of caries prevention tools. It has got a lot of attention since its introduction in the 1970s because of its ability to prevent and arrest caries, as well as its excellent antibacterial and anti‐plaque action. SDF reduces acid production by microorganisms, decreases the Streptococcus mutans count, biofilm formation, increases enamel resistance, and promotes dentinal tubule obliteration when applied to the dental surface. SDF also assists in the remineralization of dentin. A biannual application of 38% SDF has been effective at preventing dentin demineralization. This “silver bullet” can be seen as an alternative for caries prevention in special health care needs children which is minimally invasive and safe. Along with the advantages, there are some disadvantages, and work has been carried out to explore the use of silver nanoparticles (SNP) as anticaries agents to shield the teeth from aesthetic damage caused by Silver diamine fluoride. SNPs are identified to have the potential to prevent and inhibit dental caries while not discoloring demineralized dental enamel. SNPs have a greater surface area for interaction with microorganisms than other particles, making them more effective antimicrobial agents. Fluoride combined with SNP solution has a synergistic effect that promotes enamel remineralization while also acting as a bactericidal agent against cariogenic microorganisms. This review aims to bring out the various advantages and disadvantages related to the use of SDF and SNPs to aid in future research.

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Paradigm shift in the effective treatment of caries in schoolchildren at risk

Abstract: The SDF technique showed better results than IRT for the arrest of cavities in deciduous teeth, indicating that its use for underprivileged communities may justify a paradigm shift in paediatric dentistry.

Cited by 87 publications

References 13 publications

Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis

Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis

The use of silver diamine fluoride in a children's hospital: Critical analysis and action protocol

The Synergism of Silver and Fluoride: A New Arsenal in Caries Management

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