Paracoccidioidomycosis mortality in Brazil (1980-1995)

Coutinho, Ziadir Francisco; Silva, Delson; Lazéra, Márcia dos Santos; Petri, Valéria; Oliveira, Rosely Magalhães de; Sabroza, Paulo Chagastelles; Wanke, Bodo

doi:10.1590/s0102-311x2002000500037

Cited by 252 publications

(228 citation statements)

References 11 publications

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“…Southeast, midwest, and south regions have more information, believing that the incidence of paracoccidioidomycosis (PCM) in these endemic areas vary from 3 to 4 cases per million up to 1 to 3 cases per 100,000 inhabitants per year 9 . Although considered rare in the Amazon, in the last two or three decades, the number of cases has been increasing, especially in areas recently occupied, with large areas of deforestation for agricultural activities, livestock, and eucalyptus planting 10 .…”

Section: Article/artigomentioning

confidence: 99%

Paracoccidioidomycosis in the state of Maranhão, Brazil: geographical and clinical aspects

Matos

Santos

Silva

et al. 2012

Rev. Soc. Bras. Med. Trop.

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.3% of cases proving to be important areas for study. The western region, with a prevalence of 10.8/100,000 inhabitants, has a significantly higher proportion of cases than the northern, southern, and eastern regions (p < 0.05). The occurrence was higher in men with 89.3% of cases, and the male-to-female ratio was 8.4:1. The majority of patients were older than 20 years, lived in rural areas, and had farming or soil management as main occupation (73.8%). At CREDIP, 29 cases were diagnosed, of which 26 (89.6%) had multifocal manifestations. Mucous tissues were involved more (75.8%) frequently, followed by lymph nodes, skin, and lungs with 65.5%, 39% and 37.9 %, respectively. The diagnosis was made by combining direct examination, culture, and histopathology. Conclusions: The study shows the geographical distribution and the epidemiological and clinical aspects of paracoccidioidomycosis, revealing the significance of the disease to the State of Maranhão.

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Section: Article/artigomentioning

confidence: 99%

Paracoccidioidomycosis in the state of Maranhão, Brazil: geographical and clinical aspects

Matos

Santos

Silva

et al. 2012

Rev. Soc. Bras. Med. Trop.

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“…Helena Duani [1] , Vinícius Rodrigues Taranto Nunes [2] , Anísio Borges Assumpção [2] , Isadora Sofia Borges Saraiva [1] , Rodrigo Macedo Rosa [2] , Augusto Motta Neiva [2] and Ênio Roberto Pietra Pedroso [1] [1]. Setor de Infectologia, Hospital das Clinicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG. [2].…”

Section: Bilateral Paracoccidioidomycotic Iliopsoas Abscess Associateunclassified

“…Its prevalence is greater among males from 30 to 60 years old, and lungs are the most frequent compromised organs. Its acute/subacute form with generalized lesions involves multiple organs and is rare and severe 1,2 .…”

Section: Bilateral Paracoccidioidomycotic Iliopsoas Abscess Associatementioning

confidence: 99%

Bilateral paracoccidioidomycotic iliopsoas abscess associated with ileo-colonic lesion

Duani

Nunes

Assumpção

et al. 2012

Rev. Soc. Bras. Med. Trop.

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FIGURE 1 -Colonoscopy revealing the cecum and the ileocecal valve, a large ulcer, and an ulcer with fibrin (arrows). Revista da Sociedade Brasileira de Medicina Tropical 45(5):649-651, Sep-Oct, 2012Case Report ABSTRACT This case report shows the clinical development of a patient with systemic paracoccidioidomycosis presenting with lymphatic-intestinal manifestation. The patient initially had a substantial clinical improvement but had a recrudescence after six months of sulfamethoxazoletrimethoprim oral treatment, with the emergence of feverish syndrome, lumbar pain, and intermittent claudication, characterizing a bilateral iliopsoas muscle abscess, necessitating clinicosurgical therapeutics.Keywords: Paracoccidioidomycosis. Psoas abscess. Paracoccidioides brasiliensis.fungal smear; normal renal and hepatic function panels; and negative microbiological stool tests. An abdominal and pelvic computed tomography (CT) demonstrated mesenteric lymphadenomegaly, with a hypodense center. Colonoscopy evidenced multiple deep ulcers with changeable sizes and forms along the whole colon, intercalated by normal mucosa, and a deformed ileocecal valve, which favored the diagnosis of infectious ulcerative pancolitis (Figure 1). Anatomopathological examination of the colonic mucosa revealed some areas of erosion covered in fibrino-leukocytic exudate, inflammatory infiltrate in corion, with some multinucleated giant cells, and lots of round shaped yeast, in various sizes, compatible with ileum-colonic PCM (Figure 2). A biopsy of a cervical lymph node also was performed, and in the anatomopathological examination, we found the Paracoccidioides brasiliensis, with non-caseating granulomas containing multinucleated giant cells and epithelioid histiocytes, presenting a steering wheel shape, compatible with PCM granulomatous lymphadenitis. During hospitalization, the patient was treated with venous sulfamethoxazole-trimethoprim (SMX-TMP) and amphotericin B (amphoB) deoxycholate, receiving a cumulative dose of 1,900mg after www.scielo.br/rsbmt 650 Duani H et al -Bilateral paracoccidioidomycotic iliopsoas abscess DISCUSSION 38 days. A complete regression of lymphadenopathy occurred, the patient gained weight, and the diarrhea ceased. After 40 days from admission, he was discharged, with a prescription of a daily use of SMX-TMP 800 + 160mg.The patient returned 40 days later, presenting recrudescence of the initial symptoms, including pain in the left hip, limited extension of the homolateral hip, limping, and fever. Furthermore, cultures were obtained, and an anatomopathological examination of an inguinal lymph node biopsied revealed Paracoccidioides brasiliensis. He was rehospitalized and treated with amphoB plus oral itraconazole and sulphadiazine.Abdominal and pelvic CT showed mesenteric lymphadenomegaly, enlargement of the left iliac and psoas muscles, with inner voluminous liquefaction, which extended from the level of the third lumbar vertebra (L3) to the pelvis. Moreover, a smaller collection was observed in the right psoas muscle at...

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“…Blood cultures may also occasionally yield positive results for patients presenting with overwhelming infection (88). Urine fungal culture could be useful for the diagnosis of disseminated coccidioidomycosis.…”

Section: Fungal Infections Infections Caused By Coccidioides Immitismentioning

confidence: 99%

“…It has been reported only in Latin America, from Mexico (23°N) to Argentina (34°S), although it is not present in all countries within this area (Chile and some of the Caribbean Islands are not affected). The majority of cases have found in Brazil, where there is an annual incidence rate of 10 to 30 per million inhabitants (88). The disease has two main clinical presentations, a more frequent chronic adult form and the acute/subacute, more severe juvenile form (95).…”

Section: Other Regional Fungal Infectionsmentioning

confidence: 99%

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

et al. 2008

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SUMMARY In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included.

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Paracoccidioidomycosis mortality in Brazil (1980-1995)

Cited by 252 publications

References 11 publications

Paracoccidioidomycosis in the state of Maranhão, Brazil: geographical and clinical aspects

Paracoccidioidomycosis in the state of Maranhão, Brazil: geographical and clinical aspects

Bilateral paracoccidioidomycotic iliopsoas abscess associated with ileo-colonic lesion

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

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