Panniculitis–an unusual cutaneous manifestation of systemic sclerosis

Almeida, Mirtha Sosa; Lima, Sakamoto; Carvalho, Leonardo Lamarca de; Almeida, João Vicente Moreira; Santos, Lina Gomes dos; Rolim, João Rubens Agostinho; Rocha, Tarciso

doi:10.1111/j.1600-0560.2009.01356.x

Cited by 14 publications

(11 citation statements)

References 11 publications

(21 reference statements)

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“…Furthermore, lipomembranous changes were observed in the biopsy specimens taken from the forearm. In another case, a biopsy from the abdominal hard hyperchromic plaque with coalescent and painful nodules revealed lipomembranous panniculitis [6]. In the present case, lipomembranous changes were observed in the specimens from both forearm and finger unrelated with the lesion of NCFN.…”

Section: Sirsupporting

confidence: 54%

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Lipomembranous changes (membrano-cystic lesions) in the extremities of a patient with systemic sclerosis

Matsumura¹,

Yamamoto²

2018

Our Dermatol Online

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Section: Sirsupporting

confidence: 54%

“…Snow et al reported three cases of morphea in their series, which presented with lipomembranous changes on the morpheaform plaques of the back, legs, and calf [4]. To date, only a few cases of SSc similar to ours were reported [5,6]. In one case, mobile nodules appeared on the forearm, and histological examination revealed NCFN [5].…”

Section: Sirmentioning

confidence: 65%

Lipomembranous changes (membrano-cystic lesions) in the extremities of a patient with systemic sclerosis

Matsumura¹,

Yamamoto²

2018

Our Dermatol Online

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“…Most lesions present with indurated, subcutaneous lesions in the lower extremities 7. Panniculitides are less commonly seen in the arms, thighs, calves and gluteus 8 9. One case report described a woman presenting with panniculitis of the arm who was subsequently diagnosed with diffuse SSc 9.…”

Section: Discussionmentioning

confidence: 99%

Limited systemic sclerosis initially presenting with mesenteric panniculitis

Arroyo-Ávila

Vilá

2014

BMJ Case Reports

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Mesenteric panniculitis pertains to a group of uncommon disorders named sclerosing mesenteritis that present with different levels of inflammation and fibrosis of the small bowel mesentery. It is associated with abdominal surgeries, trauma, malignancies, infections and connective tissue diseases. To the best of our knowledge, no cases of sclerosing mesenteritis have been reported in patients with systemic sclerosis. We present a case of a 61-year-old woman who had incidental CT findings of mesenteric panniculitis. Diagnosis was confirmed by biopsy that showed fat necrosis. On further review she had a 1-year history of Raynaud's phenomenon. Physical examination showed sclerodactyly. She had elevated anticentromere antibodies and skin biopsy was consistent with scleroderma. She was diagnosed with limited systemic sclerosis and was treated with D-penicillamine. After 6 years of follow-up, the mesenteric panniculitis and systemic sclerosis both remained stable. This case highlights the importance of considering rheumatic diseases in the differential diagnosis of sclerosing mesenteritis.

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“…Panniculitis[13] and cutaneous hyperpigmented reticulate scleroderma[14] are some recently described unusual cutaneous manifestation of SSc. We did not find any such cases in the present series.…”

Section: Discussionmentioning

confidence: 99%

Mucocutaneous and demographic features of systemic sclerosis: A profile of 46 patients from Eastern India

et al. 2012

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Background:Systemic sclerosis (SSc) is a multisystem connective tissue disorder of uncertain etiology. The clinical picture is frequently dominated by prominent cutaneous manifestations that have diagnostic and prognostic significance. The objective of the present study was to find out the demographic profile and the relative frequencies and characteristics of different mucocutaneous features of SSc in a group of patients from eastern India. In addition, we sought to compare the frequency and pattern of the findings in the limited versus the diffuse variety of the disease.Materials and Methods:This was a cross-sectional, clinical observational study. Consecutive patients of SSc attending the dermatology O.P.D. of a tertiary care hospital of eastern India over 3 years were enrolled to the present study.Results:A total of 46 patients (41 females and 5 males; mean age 29.6±12.3 years) of SSc were evaluated. Among mucocutaneous manifestations Raynaud's phenomenon was present in 39 (84.8%) patients. Other cutaneous features included dyspigmentation (40, 86.9%), sclerodactyly (38, 82.6%), inability to open the mouth (38,82.6%), mat-like telangiectasia (11,23.1%), fingertip ulceration and scarring (29,63%), cutaneous calcinosis (1,2.2%), digital gangrene in (2,4.3%), generalized pruritus (4,8.7%), cutaneous small vessel vasculitis (2,4.3%), chronic urticaria (2,4.3%), flexion contractures of the fingers (13,28.3%), and amputation of the digits (3,6.5%). Mucosal changes were observed in 10 (21.7%) patients and nail changes were seen in 13 (28.2%) patients. Diffuse cutaneous SSc was noted in 27 (58.7%) patients and limited cutaneous SSc was seen in the remainder. Thirty-six (78.2%) patients tested positive for ANA.Conclusion:The present study provides a snapshot of the spectrum of the demographic and mucocutaneous manifestations of SSc in the eastern Indian population. We have not observed any statistically significant differences between dcSSc and lcSSc in terms of mucocutaneous manifestations in the studied population.

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Panniculitis–an unusual cutaneous manifestation of systemic sclerosis

Cited by 14 publications

References 11 publications

Lipomembranous changes (membrano-cystic lesions) in the extremities of a patient with systemic sclerosis

Lipomembranous changes (membrano-cystic lesions) in the extremities of a patient with systemic sclerosis

Limited systemic sclerosis initially presenting with mesenteric panniculitis

Mucocutaneous and demographic features of systemic sclerosis: A profile of 46 patients from Eastern India

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