Pancreatitis aguda asociada con hipercalcemia

Tun-Abraham, Mauro Enrique; Martínez-Ordaz, José Luis; Obregón-Guerrero, Gabriela; Romero-Espinoza, Larry; Valencia-Jiménez, Javier

doi:10.1016/j.circir.2015.05.006

Cited by 11 publications

(13 citation statements)

References 11 publications

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“…The incidence of acute pancreatitis associated with hyperparathyroidism is reported to be <10%. [ 3 4 ] Although the actual causal relationship between hypercalcemia and pancreatitis has been a topic of debate, detection of hypercalcemia points to a differential diagnosis of primary hyperparathyroidism as was encountered in our patient due to a giant parathyroid adenoma.…”

Section: Discussionmentioning

confidence: 70%

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A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Raghunandan

Ramshankar

2016

Indian J Nucl Med

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Parathyroid adenomas are usually small in size; (weighing 70 mg–1 g) those weighing more than 2–3 g are classified as giant parathyroid adenomas. Giant parathyroid adenomas are in fact rarely encountered among patients with primary hyperparathyroidism. They are believed to have distinct clinical and biochemical features related to specific genomic alterations. We chanced to manage a unique and possibly the first case of giant parathyroid adenoma (6 cm diameter and weighing 20 g) presenting with recurrent episodes of pancreatitis and discuss its surgical management with an added emphasis on the role of nuclear imaging in its preoperative localization. Our case demonstrates that clinicians should have a high index of suspicion of primary hyperparathyroidism in patients presenting with recurrent episodes of pancreatitis. Timely diagnosis, appropriate preoperative localization techniques, which would include a parathyroid scintigraphy and a focused surgical intervention are crucial to resolve complications and improve outcomes.

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Section: Discussionmentioning

confidence: 70%

“…Further it is believed that following aggressive medical management of acute pancreatitis, parathyroidectomy can improve the clinical outcome and prevent further recurrences of pancreatitis. [ 4 ]…”

Section: Discussionmentioning

confidence: 99%

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Raghunandan

Ramshankar

2016

Indian J Nucl Med

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“…Hypercalcemia is a widely recognized cause of acute pancreatitis (1,10). However, only one previous report describes excessive antacid administration as the etiology (2).…”

Section: Discussionmentioning

confidence: 99%

“…Hypercalcemia is a well-recognized etiology of acute pancreatitis, commonly associated with primary hyperparathyroidism (1). However, antacid-induced milk-alkali syndrome as a cause of acute pancreatitis has only been described once (2).…”

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confidence: 99%

Hypercalcemia secondary to excessive self-medication with antacids causing acute pancreatitis: a case report

2019

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Excessive self-medication with over-the-counter drugs is an issue commonly encountered by health care professionals. It can result in uncommon presentations of life-threatening illnesses. These medications are frequently overlooked by clinicians when taking histories from patients, and their risks are often downplayed. We present the case of a 35-year-old woman with acute pancreatitis secondary to hypercalcemia. This condition occurred due to long-term excessive self-administration of calcium-rich antacid tablets. Her clinical course involved multifactorial rebound hypocalcemia after treatment and multiple complications from the abuse of other non-prescription medications. Acute pancreatitis secondary to antacid-induced milk-alkali syndrome has been minimally reported in the literature. There are no reports describing rebound hypocalcemia as a complication of its treatment or presenting this pathology in the context of multiple over-the-counter drug abuse. This case highlights the importance of taking thorough drug histories, including non-prescription medications, in acute clinical assessments.

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“…In four previous cases, patients were diagnosed by computed tomography, cervical ultrasound, and Sestamibi parathryoid scintigraphy as having parathyroid adenomas. Three of the four patients experienced complications (two instances of pseudocysts and one of pancreatic necrosis), but none of them had recurrent bouts of pancreatitis after being receiving treatment [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Severe Acute Pancreatitis as an Index Clinical Manifestation of Parathyroid Adenoma

Sunkara¹,

Caughey²,

Rawla³

et al. 2018

Cureus

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Hypercalcemia due to primary or secondary hyperparathyroidism is a rare and obscure cause of acute pancreatitis. Although a rare occurrence to begin with, hyperparathyroidism commonly manifests with symptoms of hypercalcemia. Thus, it would reason that a patient might develop pancreatitis by way of hypercalcemia due to primary or secondary hyperparathyroidism. We present a case of an 88-year-old female with acute pancreatitis and only after an extensive work-up, was it determined that her severe acute pancreatitis resulted from primary hyperparathyroidism caused by a left parathyroid adenoma.

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Pancreatitis aguda asociada con hipercalcemia

Cited by 11 publications

References 11 publications

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

A rare case of giant parathyroid adenoma presenting with recurrent episodes of pancreatitis

Hypercalcemia secondary to excessive self-medication with antacids causing acute pancreatitis: a case report

Severe Acute Pancreatitis as an Index Clinical Manifestation of Parathyroid Adenoma

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