Pancreatic Tail Schwannoma in a 44-Year-Old Male: A Case Report and Literature Review

Abu‐Zaid, Ahmed; Azzam, Ayman; Al-Shaar, Hussam Abou; AlShammari, Abdullah; Amin, Tarek; Mohammed, Shamayel

doi:10.1155/2013/416713

Cited by 11 publications

(8 citation statements)

References 22 publications

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“…EUS-FNA can often obtain only very small specimens, and there have been some reports stating that only a small proportion of histologically proven schwannomas can be diagnosed correctly using EUS-FNA, which imposes a massive limitation. 4 However, in this case, EUS-FNA did provide an accurate diagnosis, resulting in an appropriate treatment. Development of a new EUS-FNA device would be possible to achieve more accurate diagnosis.…”

Section: Discussionmentioning

confidence: 62%

A Case of Pancreatic Schwannoma Diagnosed Preoperatively by Endoscopic Ultrasonography-Guided Fine Needle Aspiration and Treated with Laparoscopic Surgery

Hayashi

Tsuchiya

Ikarashi

et al. 2018

Journal of Pancreatic Cancer

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Background: Pancreatic tumors are often difficult to diagnose in atypical cases, and a pancreatic schwannoma is very rare. We present a case of pancreatic schwannoma with calcification diagnosed preoperatively by endoscopic ultrasonography (EUS)-guided fine needle aspiration (FNA) and treated with laparoscopic distal pancreatectomy.Presentation: A 72-year-old-woman was admitted to our hospital due to a 6 × 4.5 cm large tumor in the pancreatic tail. Imaging modalities revealed that the tumor was hypovascular and gradually enhanced with calcification, but was without cystic lesions. EUS revealed the tumor had a clear boundary with a low echoic mass. EUS-FNA was performed and spindle-shaped cells that were immunopositive for S-100 and negative for c-kit, CD34, and desmin were detected, resulting in a diagnosis of schwannoma. Laparoscopic distal pancreatectomy with splenectomy was safely performed without recurrence for a year.Conclusions: Schwannoma is very rare; however, characteristics of the tumor, such as calcification, can help the diagnosis and, if possible, EUS-FNA should be performed for an appropriate treatment decision.

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Section: Discussionmentioning

confidence: 62%

A Case of Pancreatic Schwannoma Diagnosed Preoperatively by Endoscopic Ultrasonography-Guided Fine Needle Aspiration and Treated with Laparoscopic Surgery

Hayashi

Tsuchiya

Ikarashi

et al. 2018

Journal of Pancreatic Cancer

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“…Only one case of pancreatic schwannoma was treated using minimally invasive laparoscopic surgery (1.47%)[21]. Enucleation has been reported in 10 (14.71%) cases.…”

Section: Discussionmentioning

confidence: 99%

“…Surgery is the curative treatment for pancreatic schwannomas, and most cases are treated by laparotomy. Only one case of pancreatic schwannoma was treated using minimally invasive laparoscopic surgery (1.47%)[ 21 ]. Enucleation has been reported in 10 (14.71%) cases.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment of a pancreatic schwannoma by spleen-preserving distal pancreatectomy

et al. 2017

WJG

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Schwannomas are neurogenic tumors that arise from the neural sheaths of peripheral nerves. These tumors can be located in any area of the human body; the most common locations are the head, neck, trunk and extremities. Pancreatic schwannomas are very rare. Over the past 40 years, only 67 cases of pancreatic schwannomas have been reported in the English literature. Here we present a case of pancreatic schwannoma in a 62-year-old male. The tumor was revealed by ultrasound and computed tomography in the neck and body of the pancreas. An accurate diagnosis was difficult to obtain preoperatively. The patient consented to the performance of a laparotomy, and the mass was found in the neck and body of the pancreas and successfully treated using a spleen-preserving distal pancreatectomy with splenic artery and vein preservation. The procedure has only been reported in one other case of pancreatic schwannoma; here we present the second reported case. Macroscopically, the tumor was well circumscribed, gray-white in color and 3.3 cm × 2.8 cm in size. Microscopically, the tumor cells were spindle-shaped and had a palisading arrangement with no atypia, which are results compatible with a benign tumor. Both hypercellular and hypocellular areas were visible. Immunohistochemically, the tumor cells were strongly positive for S-100 protein. The tumor was definitively diagnosed as a schwannoma of the pancreatic neck and body. The patient was followed for 72 mo and has been doing well without any complications.

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“…Schwannomas usually grow, in descending order of frequency, in the lower extremity, upper extremity, trunk, head and neck, retroperitoneum, mediastinum, and pelvis. 3 , 4 …”

Section: Introductionmentioning

confidence: 99%

Enlarging Pancreatic Schwannoma: A Case Report and Review of the Literature

Duma

Ramirez

Young

et al. 2015

Clinics and Practice

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A 72-year-old female presented with dyspepsia for 2 years and an incidental mass in the head of the pancreas on abdominal computed tomography (CT) scan. Patient had multiple negative endoscopic ultrasound guided biopsies. She was followed up for 3 years with serial imaging until an abdominal CT scan showed an increase in size of the pancreatic mass. Physical examination was unremarkable. Laboratory tests including tumor markers were normal. Given the enlarging size of the mass and its impingement on the portal vein, the consensus was to proceed with surgery. Histology revealed a 3.5 cm mass showing a spindle cell neoplasm with mild atypia. The lesion was well defined and nerve tissue was noted at the periphery. On immuno-stains, the spindle cells were positive for S-100 protein and negative for pan-cytokeratin, CD-34, CD-117, smooth muscle actin and Melan A, consistent with the diagnosis of a pancreatic schwannoma.

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Pancreatic Tail Schwannoma in a 44-Year-Old Male: A Case Report and Literature Review

Cited by 11 publications

References 22 publications

A Case of Pancreatic Schwannoma Diagnosed Preoperatively by Endoscopic Ultrasonography-Guided Fine Needle Aspiration and Treated with Laparoscopic Surgery

A Case of Pancreatic Schwannoma Diagnosed Preoperatively by Endoscopic Ultrasonography-Guided Fine Needle Aspiration and Treated with Laparoscopic Surgery

Successful treatment of a pancreatic schwannoma by spleen-preserving distal pancreatectomy

Enlarging Pancreatic Schwannoma: A Case Report and Review of the Literature

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