Pancreatic histological studies in mice induced by alloxan and steeping okra coffee (Abelmoschus esculentus [L.] Moench)

Anggraeni, Indiana Gita; Wahid, Rahmat A Hi; Marfu'ah, Nurul

doi:10.46542/pe.2022.222.213217

Cited by 3 publications

(2 citation statements)

References 16 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gizi yang optimal dan asupan nutrisi makanan berdampak pada sistem kekebalan melalui ekspresi gen, aktivasi sel, dan modifikasi sinyal molekul. Pola makan yang seimbang akan meningkatkan sistem imunitas yang kuat yang dapat membantu menahan invasi virus (31) (32,33).…”

Section: Hasil Dan Pembahasanunclassified

Gambaran tingkat pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta terhadap COVID-19

Wahid,

Karimatulhajj,

Fitriani

et al. 2024

Pharmasipha

View full text Add to dashboard Cite

The Corona Virus Disease 2019 (COVID-19) pandemic causes an increase in morbidity and mortality and affects the lives of global people. Knowledge of diseases, especially COVID-19, influences community compliance with control measures. Assessment of public knowledge, especially students during the pandemic crisis, is critical in attempting to overcome this outbreak. This study was conducted to assess the knowledge of first-year students at Universitas PGRI Yogyakarta towards COVID-19. Increased knowledge and awareness of students about COVID-19 is expected to break the chain of COVID-19 spread or social transmission. Preventive measures for the spread of COVID-19 can be carried out by carrying out handy hygiene, social distancing, wearing masks, and increasing the immune system and balanced nutrition. The research method used was a cross-sectional descriptive study. The sampling technique was non-random sampling with purposive sampling. Collecting data using an online questionnaire through social media networks consists of three main parts: socio-demographics, information sources, and knowledge of COVID-19. A total of 226 first-year students were included in the study; 71 (31.4%) were male, and 155 (68.6%) were female. The students mostly came from the non-health science field, which was 198 (87%) in amount, and aged 17-19 years were159 persons (70.4%). The results showed that the level of knowledge of students was classified as good (39.4%), sufficient (41.6%), and (19.0%) less. This research can conclude that the level of knowledge at Universitas PGRI Yogyakarta is sufficient, so it is necessary to increase understanding related to COVID-19 through continuous and intensive online education in the campus environment. Keywords: COVID-19, level of knowledge, first-year pharmacist students, Universitas PGRI Yogyakarta ABSTRAK Pandemik Corona Virus Disease 2019 (COVID-19) menyebabkan peningkatan morbiditas dan mortalitas serta mempengaruhi kehidupan masyarakat global. Kepatuhan masyarakat terhadap tindakan pengendalian dipengaruhi oleh pengetahuan terhadap penyakit khususnya COVID-19. Penilaian pengetahuan masyarakat khususnya mahasiswa selama krisis pandemik sangat penting dalam upaya untuk mengatasi wabah ini. Penelitian ini dilakukan untuk menilai pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta terhadap COVID-19. Meningkatnya pengetahuan dan kesadaran mahasiswa akan COVID-19 diharapkan dapat memutus rantai penyebaran COVID-19 atau transmisi sosial. Tindakan preventif penyebaran COVID-19 bisa dilakukan dengan melakukan handy hygiene, social distancing, menggunakan masker, dan meningkatkan sistem imun serta gizi seimbang. Metode penelitian yang digunakan adalah studi deskriptif dengan desain cross sectional. Teknik pengambilan sampel secara non random sampling dengan jenis purposive sampling. Pengambilan data menggunakan koesioner online melalui jejaring media sosial yang terdiri dari tiga bagian utama: sosio-demografi, sumber informasi, dan pengetahuan terhadap COVID-19. Sebanyak 226 mahasiswa tahun pertama dilibatkan dalam penelitian ini, 71 (31,4%) adalah laki-laki, dan 155 (68,6%) adalah perempuan. Latar belakang mahasiswa sebagian besar berasal dari bidang ilmu non Kesehatan berjumlah 198 (87%) dan berusia 17-19 tahun 159 (70,4%). Hasil penelitian menunjukkan tingkat pengetahuan mahasiswa yang tergolong baik (39,4%), cukup (41,6%), dan (19,0%) kurang. Penelitian ini dapat disimpulkan bahwa tingkat pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta tergolong cukup sehingga diperlukan peningkatan pemahaman terkait COVID-19 melalui edukasi secara online yang berkelanjutan dan intensif di lingkungan kampus. Kata Kunci: COVID-19, Tingkat Pengetahuan, Mahasiswa Tahun Pertama, Universitas PGRI Yogyakarta

show abstract

Section: Hasil Dan Pembahasanunclassified

Gambaran tingkat pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta terhadap COVID-19

Wahid,

Karimatulhajj,

Fitriani

et al. 2024

Pharmasipha

View full text Add to dashboard Cite

show abstract

“…The common ingredients for pulp devitalization have numerous serious adverse effects that need to be considered, so there is a need for a safer alternative, especially from natural ingredients. Natural ingredients are currently widely used as treatment, especially in oral problems (Anggraeni et al, 2022) (Wahid & Damarwati, 2021) (Lestari et al, 2021), such as combination of jatropha curcas (Jatropha curcas L.) and red betel leaf extract (Piper crocatum). Ethnopharmacologically, jatropha latex has benefits as a nerve-killing agent in teeth (Tanumihadja et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Formulation and Evaluation of Pulp Devitalization Paste Combination of Jatropha Curcas L. and Piper Crocatum Leaves Extract

Damarwati

Wahid²,

Primasari³

et al. 2022

Media Farmasi

View full text Add to dashboard Cite

Dental caries requires operative techniques such as pulp devitalization, but pulp devitalization materials that are often used by dentists have serious adverse effects that need to be considered, such as gingival injury and alveolar bone necrosis. Hence, the aim of the present study was to evaluate and formulation of herbal alternatives to pulp devitalization from a combination of Jatropha curcas (Jatropha curcas L.) and red betel leaf extract (Piper crocatum) in the form of a paste and then conducting physical evaluation tests, Cyclooxygenase-2 (COX-2) tests, and also histopathological picture tests to the sample. The formulation of the pasta sample was carried out by the trituration method. Formulation I (FI) contained 25% of Jatropha resin, 0.25% red betel leaf extract, and 25% Jatropha resin, 0.5% red betel leaf extract for Formulation II (FII). The paste produced was then evaluated for physical properties which consisted of organoleptic, homogeneity, pH, spreadability, adhesion, and in vivo anti-inflammatory effect (animal models). In the COX-2 expression test, FI has a COX-2 expression percentage value of 0.38% and a COX-2 suppression percentage value of 0.62%, while FII has a COX-2 expression percentage value of 0.59% and suppression of COX-2 of 0.41%. The optimal concentration of the paste formulation is the paste with a combination of 25% jatropha latex and 0.25% red betel leaf extract had been shown to have potential as an alternative to pulp devitalization.This is an open access article under the CC-BY-SA license.

show abstract

Therapeutic Potential of Black Seed Oil to Nuclear Factor Kappa B Levels of Patients with Metabolic Syndrome Risk

A Hi Wahid,

Darmawan

2023

RJPT

View full text Add to dashboard Cite

Herbal medicine is one of the most used adjuvant and alternative therapies by people with metabolic syndrome (MetS) risk. This is alongside conventional MetS risk treatments. Black Seed Oil(BSO) is a medicinal plant most widely used worldwide as the most excellent form of healing medicine. This study aimed to evaluate the effect of BSO as adjuvant therapy on levels of NF-κB in patients with MetS risk. This prospective was conducted at Jetis I Public Health Center (PHC), Yogyakarta, Indonesia. After confirmation of diagnosis, sixty-two patients who fulfilled the inclusion and exclusion criteria were enrolled in this study. Approval from the institutional ethical committee was also obtained. The patients with MetS risk were divided into two groups (n=31). In group I (the BSO group), the patients have advised BSO 3mL/day for 20 days. In group II (the Control group), the patients have advised a placebo for 20days. The level of NF-κB was estimated using the enzyme-linked immunosorbent assay (ELISA) method. The median values between groups were tested with Mann-Whitney with a significance of P=<0.05 (95%). The favorable impact of BSO was seen in almost all variables, but the results were not statistically significant (P>0.05). Adjuvant therapy of BSO doses of 3 mL/day could not increase levels of NF-κB in the patients with MetS risk at Jetis I PHC, Yogyakarta, Indonesia. A larger study with adequate sample size and long-term supplementation with BSO is recommended.

show abstract

Pancreatic histological studies in mice induced by alloxan and steeping okra coffee (Abelmoschus esculentus [L.] Moench)

Cited by 3 publications

References 16 publications

Gambaran tingkat pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta terhadap COVID-19

Gambaran tingkat pengetahuan mahasiswa tahun pertama di Universitas PGRI Yogyakarta terhadap COVID-19

Formulation and Evaluation of Pulp Devitalization Paste Combination of Jatropha Curcas L. and Piper Crocatum Leaves Extract

Therapeutic Potential of Black Seed Oil to Nuclear Factor Kappa B Levels of Patients with Metabolic Syndrome Risk

Contact Info

Product

Resources

About