Pamamycin: A new antibiotic and stimulator of aerial mycelia formation.

McCann, P A; Pogell, Burton M.

doi:10.7164/antibiotics.32.673

Cited by 88 publications

(37 citation statements)

References 6 publications

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“…18) We showed that some antibiotics inhibiting protein biosynthesis suppressed the development of aerial mycelia and the production of phytotoxins in S. scabiei and S. acidiscabies. 9) Two inhibitory substances reported here are large molecules and are non-peptidic or saccharic in character, indicating that they are a new type of inhibitor.…”

Section: Effects Of Inhibitor a On Other Phytopathogenic Streptomycesmentioning

confidence: 91%

Isolation and structural properties of aerial mycelium differentiation-inhibitory substances against Streptomyces scabiei causing potato common scab

et al. 2007

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The inhibitor of aerial mycelium differentiation in Streptomyces scabiei, a pathogen of potato common scab, was searched. An actinomycete isolated from the field was found to produce inhibitors and two active substances were isolated as single peaks with HPLC. The molecular weights of inhibitors A and B were 1156.5 and 1140.5, respectively. Numbers of functional groups in inhibitor A were estimated by derivatization reactions. Inhibitor A seems to be a non-peptidic or non-saccharic substance because enzymatic treatments with pepsin, trypsin or glycosidases did not affect the LC-MS profiles or inhibitory activity.

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Section: Effects Of Inhibitor a On Other Phytopathogenic Streptomycesmentioning

confidence: 91%

Isolation and structural properties of aerial mycelium differentiation-inhibitory substances against Streptomyces scabiei causing potato common scab

et al. 2007

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“…These results indicated one unsubstituted ring and thus the four substituents must be located on the other aromatic ring at C-1 (CHO), -2 , -3 and -4 positions. Of these substituents, the methyl group was shown to be at C-2 from NOE experiments; i.e., irradiation of the methyl signal enhanced (9%) the aldehyde signal, 6.91 (br s) a Chemical shifts are in ppm relative to internal Me 4Si. Table 2.…”

Section: Sirmentioning

confidence: 99%

Carbazomycinal and 6-methoxycarbazomycinal as aerial mycelium formation-inhibitory substances of Streptoverticillium species.

1986

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“…1) is an aerial mycelium-inducing substance that was first isolated from Streptomyces alboniger. [3][4][5][6] Although pamamycin-607 is only produced by a limited number of species, it restores or stimulates the formation of aerial mycelia in many Streptomyces spp., and also affects secondary metabolite production in several strains. 7) We examine here the effect of pamamycin-607 on the regulation of secondary metabolism.…”

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confidence: 99%