Palustroside, a coumarin glucoside ester fromLedum palustre

Oplopanphesides A-C, Three New Phenolic Glycosides from the Root Barks of Oplopanax horridus

“…IR spectra were obtained with a PerkinElmer Spectrum 100 FT-IR spectrometer with KBr pallets. The 1 H-, 13 C-, and 2D-NMR spectra were recorded on a Bruker AV-500 spectrometer (d in ppm, J in Hz) with tetramethylsilane (TMS) as an internal standard (Bruker, Germany). ESI-MS and HR-ESI-MS measurements were carried out on an Agilent 1100 series LC/MSD Trap VL mass spectrometer and an Agilent timeof-flight (TOF) mass spectrometer respectively (Agilent, U.S.A.).…”

“…The UV spectrum of 3 showed absorption Table 1. 1 H-(500 MHz) and 13 3) were clearly observed, revealing the HMG group was connected to C-6Ј of glucopyranosyl. From the above results, the structure of 3 was characterized as (Ϫ)-6Ј-O-3Љ-hydroxy-3Љ-methylglutaryl-syringin.…”

“…Analysis of the 13 C-NMR, distortionless enhancement by polarization transfer (DEPT) and heteronuclear multiple quantum correlation (HMQC) spectra revealed the presence of twenty one carbons (Table 1) with C-3Љ (70.7) revealed the existence of a 3-hydroxy-3-methylglutaryl unit (HMG) as a substructure. 13,14) (Fig. 2 13 .…”

An Efficient Copper-Catalyzed Three-Component Synthesis of 3-C-Linked Glycosyl Iminocoumarins

“…4 Glycosides in which the sugar unit is linked to a coumarin 5 pharmacophore constitute a novel class of glycosides, namely the coumarin glycosides. In accord with the intriguing biological profile of coumarins, coumarin glycosides exhibit a broad spectrum of biological activities, such as anti-inflammatory, 6 anticoagulant, 7 anticancer, 8 and antibacterial activities, 9 and they are also useful as fluorescent probes for studies on ultrafast DNA dynamics. 10 Although there are many naturally occurring O-glycosyl coumarins 11 [e.g., dauroside A (3), 12 ], the only coumarin C-glycoside that has been found in nature is dauroside D (4), 13 also known as mulberroside B, 14 which exhibits spasmolytic and hypotensive activities.…”

A new and informative [a,b,c,d] nomenclature for one-pot multistep transformations: a simple tool to measure synthetic efficiency

“…Such compounds are known to possess anti-inammatory, 61 anticoagulant, 62 anticancer, 63 anti bacterial activities 64 and they also act as useful uorescent probes for studies on ultrafast DNA dynamics.…”