“…4 Glycosides in which the sugar unit is linked to a coumarin 5 pharmacophore constitute a novel class of glycosides, namely the coumarin glycosides. In accord with the intriguing biological profile of coumarins, coumarin glycosides exhibit a broad spectrum of biological activities, such as anti-inflammatory, 6 anticoagulant, 7 anticancer, 8 and antibacterial activities, 9 and they are also useful as fluorescent probes for studies on ultrafast DNA dynamics. 10 Although there are many naturally occurring O-glycosyl coumarins 11 [e.g., dauroside A (3), 12 ], the only coumarin C-glycoside that has been found in nature is dauroside D (4), 13 also known as mulberroside B, 14 which exhibits spasmolytic and hypotensive activities.…”