Palladium complexes of N-aryl-2-pyridylamines

Synthesis of 5,5′-Diarylimino Quinoidal 2,2′-Bithiazoles

“…The reaction of 4- n -butoxyaniline with 4,4′-dibromo-5,5′-di­(pyrid-2-yl)-2,2′-bithiazole ( 3g ) (entry 24) led to no reaction. This was not surprising, since pyridines can coordinate to palladium and poison the catalytic cycle . Also, the reaction of 2-, 3-, and 4-pyridylamines with 3a proceeded only slowly (entries 9–11) and did not reach completion, often giving mixtures of unreacted dibromo- and/or monoamino bithiazoles (see SI section S4).…”

An expedient approach to enhance Mizoroki–Heck coupling reaction by infrared irradiation using palladacycle compounds

“…Phosphine ligands, especially the electron‐rich phosphines, are often toxic and sensitive to air and moisture; also phosphinite palladacycles exhibit better activity than structurally similar phosphite and phosphine complexes 14a) . Consequently, the search for easily handled, active, thermally stable and low‐cost catalysts has caused the development of phosphine‐free palladium catalysts such as palladium complexes bearing nitrogen‐donor ligands . In addition, extensive studies have shown the efficiency and robustness of palladacycles in performing Mizoroki–Heck coupling reaction …”

Application of dimeric cyclopalladated complex of tribenzylamine as an efficient catalyst in the Heck cross-coupling reaction

“…Bedford et al also showed that phosphinite palladacycles exhibited better activity than structurally similar phosphite and phosphine complexes [22]. Consequently, the search for easy handling, active, thermally stable and low-cost catalysts caused the development of phosphine-free palladium catalysts such as palladium complexes bearing nitrogen-donor ligands [30]. For several years only aryl iodides and aryl bromides were employed in Heck reaction.…”