2018
DOI: 10.1097/scs.0000000000004406 View full text |Buy / Rent full text
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Abstract: Open craniosynostosis repair is associated with high levels of pain and low utilization of nonopioid analgesics. Strategies to improve pain, decrease emesis and LOS include implementation of multimodal analgesia period and avoidance of enteral medications in the first 24 hours after surgery.

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“…We conducted this systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, in accordance with Cochrane review methods [ 19 , 20 ]. The published literature was searched on MEDLINE, Cochrane, EMBASE, and Google Scholar from inception until May 2022 without specifying a timeframe.…”
Section: Methodsmentioning
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“…We conducted this systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, in accordance with Cochrane review methods [ 19 , 20 ]. The published literature was searched on MEDLINE, Cochrane, EMBASE, and Google Scholar from inception until May 2022 without specifying a timeframe.…”
Section: Methodsmentioning
“…Ketorolac is an NSAID with an analgesic efficacy and safety similar to commonly used opioids and has been validated in cardiac, abdominal, orthopedic, urologic, neurologic, and plastic surgical procedures involving adult and pediatric populations (Watcha et al, 1992; Marín-Bertolín et al, 1997; Lieh-Lai et al, 1999; Beiter et al, 2001; Shin et al, 2001; Dsida et al, 2002; Forrest et al, 2002; Gupta et al, 2004; Cepeda et al, 2005; Lynn et al, 2007; Torgerson et al, 2008; Yassen & Sayed, 2012; Carr et al, 2018; Howard et al, 2018; Kattail et al, 2018). The analgesic effect is provided by the blockade of the cyclooxygenase (COX) system, which decreases prostaglandin synthesis.…”
Section: Introductionmentioning