2021
DOI: 10.1177/10556656211012864
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Abstract: Objective: To analyze safety and efficacy of single-dose ketorolac after primary palatoplasty (PP). Design: Consecutive cohort of patients undergoing PP, comparing to historical controls. Setting: A large academic children’s hospital. Patients, Participants: A consecutive cohort of 111 patients undergoing PP (study n = 47) compared to historical controls (n = 64). Interventions: All patients received intraoperative acetaminophen, dexmedetomidine, and opioids while the study group received an additional single … Show more

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Cited by 2 publications
(4 citation statements)
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References 56 publications
(93 reference statements)
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“…Because bleeding is such a rare event in cleft palate surgery, a larger sample size would be required to prove any significant difference between the ketorolac and nonketorolac groups. The Stein et al (2021) study also found no differences in bleeding between their ketorolac and nonketorolac groups. Our results add further evidence to support the safety of ketorolac use in cleft palate surgery.…”
Section: Discussionmentioning
confidence: 80%
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“…Because bleeding is such a rare event in cleft palate surgery, a larger sample size would be required to prove any significant difference between the ketorolac and nonketorolac groups. The Stein et al (2021) study also found no differences in bleeding between their ketorolac and nonketorolac groups. Our results add further evidence to support the safety of ketorolac use in cleft palate surgery.…”
Section: Discussionmentioning
confidence: 80%
“…This reached statistical significance with a P -value of <.001. A similar study investigating a single IV dose of ketorolac following their procedure (Stein et al, 2021) did not find this significant decrease in narcotic usage. This could be related to the difference in intervention protocols, as our study administered IV ketorolac intraoperatively and postoperatively and their protocol involved administration of a single dose of IV ketorolac postop.…”
Section: Discussionmentioning
confidence: 88%
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