Paget's disease of the orbit: before and after APD.

Buckler, Helen; Cantrill, J A; Klimiuk, P.; Anderson, D. C.

doi:10.1136/bmj.295.6613.1655

Cited by 7 publications

(3 citation statements)

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“…Aminohydroxypropylidene bisphosphonate and zoledronic acid (a potent bisphosphonate) were successfully used to treat patients who developed optic neuropathy and diplopia due to compression of cranial nerves (Buckler et al, 1987;Pane, 2007). In our patient, it was a localized disease with no compressive complications, and the diagnosis was not confirmatory before pathology report.…”

Section: Commentmentioning

confidence: 53%

“…The bony orbital disorder that affects posterior 2. aspects of the greater or lesser wings of the sphenoid bone and anterior clinoid process, causing narrowing of the superior orbital fissure and optic canal, with subsequent proptosis, limitation of eye movement, and optic neuropathy (Eretto et al, 1984;Buckler et al, 1987;Kheterpal et al, 1994;Miller at al., 1999). Skull base Paget disease may cause compressive sixth nerve palsy (Pane, 2007).…”

Section: Introductionmentioning

confidence: 98%

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Solitary Orbital Paget Disease: A Case Report

Tari

Fard

2010

Orbit

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Section: Commentmentioning

confidence: 53%

Section: Introductionmentioning

confidence: 98%

Solitary Orbital Paget Disease: A Case Report

Tari

Fard

2010

Orbit

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“…Non sono stati eseguiti studi specificatamente disegnati a valutare l'efficacia dei bisfosfonati nel prevenire le deformità scheletriche. È stata documentata in alcuni casi una riduzione delle deformità facciali dopo completa normalizzazione del turnover osseo (33,34). Malgrado la mancanza di dati controllati è raccomandabile sottoporre a terapia medica pazienti affetti da MdP con interessamento del cranio e dei segmenti scheletrici sottoposti a maggior carico meccanico (arti inferiori, bacino, rachide lombare).…”

Section: Deformità Scheletricheunclassified

Italian guidelines for the diagnosis and treatment of Paget’s disease of bone

Adami

Bartolozzi

Brandi³

et al. 2011

Reumatismo

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Paget's disease of bone is a chronic focal abnormality of bone turnover that remains totally asymptomatic over a very long period of time but that eventually ensue in bone pain and skeletal deformities. Although, in the last decade new insights have been obtained on its etiology, this remains largely obscure. Effective medical treatment (based on the use of bisphosphonates) has become available and the diagnostic procedures are now well defined. However, there remains considerable controversy regarding the hierarchy of diagnostic procedures and the medical treatment threshold. In the last few years different institution have published national guidelines, reflecting local national health systems and the available medical treatment. In this review, a working group derived from members of the SIOMMMS has examined the information available regarding the diagnosis and treatment of Paget's disease in order to develop guidelines to assist in the management of this condition. The first draft was then extensively reviewed by experts derived from the most representative scientific societies of rheumatology, internal medicine, and orthopaedic surgery. The document provides the most updated recommendations based primarily on the "evidence-based-medicine" but also on the Italian regulation for the diagnostic procedures and on the available medical treatments.Parole chiave -Morbo di Paget, bisfosfonati.

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