“…'Factors associated with serious skin reactions in children aged 12 years and under taking lamotrigine' The incidence of serious skin reactions, irrespective of cause, in children aged ≤ 12 years taking lamotrigine has been reported as being between 1 in 300 and 1 in 100 1 . We reviewed all such cases identified from clinical add-on trials. Several factors associated with the skin reactions were identified; the importance of each has yet to be determined.…”