Padrões morfológicos e critérios de malignidade do tumor venéreo transmissível aos exames citopatológico e histopatológico

Abstract

The aim of this study was to identify morphological patterns and malignancy criteria of the TVT in cytopathological and histopathological evaluations and relate these characteristics to clinical evolution and response to chemotherapy. Regarding studied animals, sixteen dogs were female and four were male. The age of the animals ranged between one and ten years old. Considering breed, 80% of the dogs were mongrel dogs and 20% were of other breeds. It was found that the cytological samples allowed a better characterization of the cell type than histological ones. The plasmacytoid was the most common morphological type of TVT, followed by the lymphocytoid and mixed standards. There was no difference among the scores for the malignancy criteria and morphological types of TVT. Regarding response to chemotherapy, no morphological type of the TVT showed any difference, but the TVT presents morphological peculiarities that may interfere with tumor behavior, especially those related to increased aggressiveness and that are observed in the plasmacytoid TVT.

Clasificación citológica de malignidad de mastocitomas en perros

“…Segundo Lima et al (2013) quando comparados a análise citológica com a histológica, pode-se observar que as amostras citológicas permitem uma maior caracterização do tipo de célula, assim como os critérios de malignidade, e ocorre menos distorção de imagem quando é comparado com amostras histológicas. A avaliação da quantidade celular foi classificada em discreta, moderada e intensa.…”

“…Em casos que o número de critérios de malignidade seja superior a três, considera-se uma neoplasia maligna (Lima et al, 2013, Braz et al, 2016.…”