Paclitaxel-induced radiation recall dermatitis

Preoperative Paclitaxel and Radiotherapy for Locally Advanced Breast Cancer: Surgical Aspects

“…Recall of the radiation effects by both paclitaxel and Adriamycin likely contributed to this, and they must be considered a source of potential problems in regimens involving preoperative radiation. [21][22][23][24][25] Modifying the protocol to twice-a-week dosing eliminated the need for flap reconstruction with the associated complications.…”

Chemotherapeutic agents and the skin: An update

“…The latter agent is present in a higher concentration in the formulation of paclitaxel than other drugs and is known to induce histamine release from mast cells. 173 Other cutaneous adverse events reported with paclitaxel therapy include radiation recall dermatitis, [175][176][177] erythema multiforme, 178 and onycholysis. 179 Only one case of acral erythema has been reported.…”

A Docetaxel-Induced Rash on a Radiotherapy Port

“…The two cytotoxic agents of this group, docetaxel and paclitaxel, have been previously involved in a series of radiation recall reactions. [10,[23][24][25][26][27][28][29][30] Even when the immediate radiation effects have subsided, the irradiated skin continues to host a variety of physical and functional changes that weaken a series of skin functions. The radiation recall reaction unpredictably recurs on re-exposure to the inciting drug.…”