P91 Clearance of non AIDS-Kaposi sarcoma after removal of coexistent clear cell renal cell and chromophobe renal cell carcinomas

Giatrakou, S.; Leodara, V.; Siatelis, Argyris; Papadavid, E.; Theodoropoulos, Kleanthis; Safioleas, K.; Stamatakos, Michael D.; Stavrianeas, N.

doi:10.1097/01.cmr.0000382925.70143.e8

Cited by 1 publication

(9 citation statements)

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“…In addition, another case of synchronous aIDS-related KS with renal cell adenocarcinoma in a 42-year-old homosexual male was reported (9). the present case is the first report of synchronous classic KS and clear cell rCC, followed by the case of Giatrakou et al (7).…”

Section: Discussionsupporting

confidence: 56%

“…In the literature, the association of KS with various diseases and cancers has been discussed ( 4 , 7 , 15 ). Multicentric Castleman disease (MCD) refers to a lymphoproliferative disorder that is associated with secondary B-cell lymphoma development.…”

Section: Discussionmentioning

confidence: 99%

“…Iscovic et al ( 19 ) conducted a study on 1,000 Jewish patients with classic KS and found that 61 cases were affected by a second neoplasm, and increasing risks of non-Hodgkin's lymphoma and cutaneous malignant melanoma were detected. The simultaneous appearance of KS and RCC is a very infrequent condition ( 7 ). To the best of our knowledge, only three such cases have been published to date.…”

Section: Discussionmentioning

confidence: 99%

“…the simultaneous occurrence of several different tumors, such as a primary tumor with a metastatic tumor or a metastatic tumor with an inflammatory lesion has been previously reported as the association of KS with several malignant diseases like lymphomas, leukemias and multiple myeloma. However, its co-existence with a solid tumor, such as renal cell carcinoma (rCC), is extremely rare (6,7). Based on the literature and to the best of our knowledge, there are only three reports available to date that mention this finding (7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

“…However, its co-existence with a solid tumor, such as renal cell carcinoma (rCC), is extremely rare (6,7). Based on the literature and to the best of our knowledge, there are only three reports available to date that mention this finding (7)(8)(9). RCC represents a heterogenous group of cancers originating from renal tubular epithelial cells.…”

Section: Introductionmentioning

confidence: 99%

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Synchronous Kaposi sarcoma and renal cell carcinoma in an elderly male patient (a very uncommon reported entity): A case report

Bapir

Shabur²,

Aghaways

et al. 2023

Med Int

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Based on the literature, there are only three reports available to date on synchronous Kaposi sarcoma (KS) and renal cell carcinoma (rCC), at least to the best of our knowledge. the present study reports a rare case of synchronous classic KS and clear cell rCC. a 69-year-old male presented with painful, purplish nodular lesions on the dorsal aspect of his hands and feet. He had no chronic medical illnesses or prior surgical interventions. an excisional biopsy of one of the lesions revealed a nodular dermal lesion with numerous vascular channels and interlacing spindle cells. a 2.5 cm-enhancing mass was found in a contrast-enhanced computed tomography scan of the abdomen, suggesting rCC or metastasis. a partial nephrectomy was performed, and the histopathological findings were consistent with clear cell RCC. the patient responded well to paclitaxel and topical imiquimod (5%), and the skin lesions disappeared. Both KS and rCC are vascular tumors, and their pathogenesis is commonly affected by an angiogenic factor known as vascular endothelial growth factor (VEGF). a complete response of KS was observed after sorafenib, an inhibitor of VEGF receptors, was administered for the treatment of metastatic renal cancer. this reinforces the fact that there is a common therapeutic and pathogenetic pathway between these two neoplasms. Synchronous KS and clear cell RCC are rare findings. Their simultaneous appearance may be triggered by the common enhancing angiogenic factor, VEGF.

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Section: Discussionsupporting

confidence: 56%