P861 Short-chain fatty acids as a marker of intestinal dysbiosis in patients with inflammatory bowel diseases

Novel Gut Microbiota Patterns Involved in the Attenuation of Dextran Sodium Sulfate-Induced Mouse Colitis Mediated by Glycerol Monolaurate via Inducing Anti-inflammatory Responses

“…5C ). Our findings were parallel to the previous data showing that the specific microbial taxa (such as Clostridia and Helicobacter ), butyric acid, Tregs, and the cross talk between them may have a predominant role in preventing DSS colitis ( 28 ).…”

“…In contrast, GML, regardless of pretreatment or cotreatment, reversed the DSS-induced dysbiosis in microbial diversity. Accordingly, butyric acid and propionic acid, which were marginally restored in the pre-GML+DSS group relative to the DSS group, could contribute to ameliorating experimental colitis ( 28 ). The aforementioned results were consistent with the previous reports that Bifidobacterium has been regarded as an acetate-to-butyrate converting organism, and the synthetic butyrate, in turn, promoted the growth of Bifidobacterium and Lactobacillus in the gut ( 34 , 35 ).…”