P1779novel Once-Daily Extended-Release Tacrolimus Versus Twice -Daily Tacrolimus in De Novo Kidney Transplant Recipients During the Early Posttransplant Period
Abstract:Background and Aims
Both under and over-dosing of tacrolimus may compromise clinical outcomes by exposing patients to either the risks of graft rejection or adverse events (AEs) associated with immunosuppressive therapy. This study is designed to compare the clinical follow-up of our kidney transplant recipients receiving once-daily, prolonged-release (PR-T; Advagraf) and twice-daily, immediate-release (IR-T; Prograf) tacrolimus in the early posttransplant period.
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