P1-S1.37 Prevalence of and risk behaviours forNeisseria gonorrhoeaein parturient women aged 15–24 in Brazil

Abstract

Methods Analyses of positivity trends were conducted using available data for opportunistic asymptomatic tests (screens) from the NCSP national dataset for 2005 to 2010 from areas that implemented screening throughout this time period. Age, sex, ethnicity, sexual behaviour, regional and venue of screen weights for the English population of 15e24-year-olds were derived (from national sources where available) and applied to the dataset. Results From 2005 to 2010 there was an increase in screens among men. There were no major changes in characteristics known to be associated with infection (year of age, sexual behavioural variables). Available data on sexual behavioural variables and ethnicity decreased over time. There were some changes in venue use over time. Weighting for 5-year age group, sex, <2 sexual partners in past 12 months, ethnicity and region lowered positivity in each year but slightly increased the decline in positivity from an average decline of 13% per year (from 11% in 2005 to 6% in 2010) to an average of 14% per year (from 10% to 4%). Additional standardisation by screening venue did not reduce the overall observed decline in positivity during this period. Differences in positivity between venues remained, but were slightly reduced, after weighting for differences in known characteristics of screened clients. Conclusions The observed decline in positivity over time among screens was not accounted for by weighting for known characteristics of those screened or changes in testing venues. Together with the consistency of declining positivity in all sub-categories this suggests that a true decline in population prevalence may have occurred. Further analyses of the potential effects of data limitations and using regression techniques with additional variables (eg, deprivation) are in progress to better understand the relationship between screen positivity and population prevalence at different levels of screening uptake in England. Background National notifiable disease data indicate that 99 of every 100 000 persons in the USA were infected with gonorrhoea in 2009, the lowest recorded gonorrhoea rate in US history. However, the extent to which declining case reports signify a reduction in prevalence is unknown. In order to better understand national gonorrhoea trends, we examined prevalence over time among men and women entering the National Job Training Program (NJTP). Methods Gonorrhoea prevalence was estimated among 16e24-yearold men and women entering the NJTP in 48 states and the District of Columbia from 2004e2009. To approximate gonorrhoea screening, only data from the 105 (85% of all 123) centers that performed gonorrhoea testing on at least 50% of the population were included. Conditional logistic regression was used to assess the probability of testing positive for gonorrhoea over time, adjusted for variables associated with gonorrhoea risk. Gonorrhoea prevalence among black women decreased from 3.6% in 2004 to 2.5% in 2009 and was 2e4 times higher than prevalence among white women during th...