P0971 Incidence of Infantile and Familial Ger in Children With Gastroesophageal Reflux Disease(gerd)

Efficacy and Safety of Lansoprazole in Adolescents with Symptomatic Erosive and Non‐erosive Gastroesophageal Reflux Disease

“…A recently completed prospective study of children found no correlation between endoscopic grade of esophagitis and symptoms of gastroesophageal reflux. Among the 54 children with symptoms of reflux 83% had grade I and 17% had grade II esophagitis (16). Children with neurologic injury, developmental disabilities or other chronic diseases tend to have a higher prevalence of gastroesophageal reflux and its complications than do children with no comorbidities (2)(3)(4).…”

“…Many of these childhood and adolescent reflux patients grow into adults with reflux disease (14)‐evidence supporting the theory that gastroesophageal reflux disease may be a life‐long disease (1,14,15). A recent prospective study of 54 children between 6 and 17 years of age (mean age, 10.3 years) revealed that 39% had histories of reflux disease during infancy (16). A family history of gastroesophageal reflux was found in 42% of the children.…”