P02.207 Bone mineral density in adult with history of treatment of anorexia nervosa

Abstract

assessed using the Hamilton Rating Scale for Depression (HAM-D). Response equaled at least a 50% decrease in the baseline HAM-D 21-item score. Remission equaled a HAM-D l7-item score of 7 or less. Differences between venlafaxine, SSRIs, and placebo for gender and age subpopulations were determined using Fisher's exact test.Results: Outcomes with each treatment were similar for all subpopulations. In both genders, venlafaxine and SSRI remission rates were superior to placebo at week 8 (all P < 0.05); additionally, venlafaxine had a higher remission rate than SSRIs in these subpopulations. With venlafaxine, response was more rapid (week 2 vs placebo, P < 0.02); by week 8, response rates were higher (61% to 79%) than with SSRls (51% to 62%) [P < 0.011.Conclusions: These data may suggest that depressed patients of both genders and ages respond similarly to available pharmacotherapies. Moreover, a more rapid response and remission are likely with venlafaxine.