P.1.h.009 Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats

Göçmez, S.S.; Demirtas, T.; Aksöz, Elif; Utkan, Tijen; Gacar, Nejat

doi:10.1016/s0924-977x(15)30340-0

Cited by 3 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, it inhibited apoptosis by reducing the expression of genes associated with apoptosis signaling pathways; protein-coding gene Bax , cytochrome - c , cas - 3 , cas - 8 , and p53 genes [ 24 , 25 ]. It was also evident that propolis protected cell membranes and prevented further deterioration of the tissue morphology associated with toxicity [ 23 , 26 , 28 , 33 , 35 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence

Zulhendri¹,

Perera

Tandean

2021

Biomedicines

View full text Add to dashboard Cite

Propolis has been used therapeutically for centuries. In recent years, research has demonstrated its efficacy as a potential raw material for pharmaceuticals and nutraceuticals. The aim of the present scoping review is to examine the latest experimental evidence regarding the potential use of propolis in protecting the brain and treating neurological disorders and injuries. A systematic scoping review methodology was implemented. Identification of the research themes and knowledge gap was performed. After applying the exclusion criteria, a total of 66 research publications were identified and retrieved from Scopus, Web of Science, Pubmed, and Google Scholar. Several key themes where propolis is potentially useful were subsequently identified, namely detoxification, neuroinflammation, ischemia/ischemia-reperfusion injury/traumatic brain injury, Alzheimer’s disease, Parkinson’s disease, and epilepsy models, depression, cytotoxicity, cognitive improvement, regenerative medicine, brain infection, and adverse effects. In conclusion, propolis is shown to have protective and therapeutic benefits in alleviating symptoms of brain and neurological disorders and injuries, demonstrated by various in vitro studies, animal models, and human clinical trials. Further clinical research into this area is needed.

show abstract

Section: Discussionmentioning

confidence: 99%

Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence

Zulhendri¹,

Perera

Tandean

2021

Biomedicines

View full text Add to dashboard Cite

show abstract

P.217 The effects of propolis on cognitive impairment in chronic unpredictable mild stress-induced depression model of rats

Göçmez

Özer

Celebi

et al. 2019

European Neuropsychopharmacology

View full text Add to dashboard Cite

Evidence on the Health Benefits of Supplemental Propolis

2019

View full text Add to dashboard Cite

Propolis is a honey-related product with reported health benefits such as improved immunity, lowered blood pressure, treated allergies and skin conditions. A literature review and narrative synthesis were conducted to investigate the evidence on the reported health benefits and future direction of propolis products. Using a predefined search strategy we searched Medline (OvidSP), Embase and Central for quantitative and qualitative studies (1990–2018). Citation, reference, hand searches and expert consultation were also undertaken. Studies of randomised control trials and observational data on humans with health-related outcomes were included. Collected data were entered into NVivo software (Version 12, QRS International) and analysed using a thematic framework and a narrative synthesis of emergent themes. A total of 63 publications were discussed. The majority were cell-based and animal studies, with a few key human trials conducted. There is significant promise for propolis as an effective antioxidant and anti-inflammatory agent with particular promise in cardiometabolic health.

show abstract

P.1.h.009 Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats

Cited by 3 publications

References 0 publications

Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence

Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence

P.217 The effects of propolis on cognitive impairment in chronic unpredictable mild stress-induced depression model of rats

Evidence on the Health Benefits of Supplemental Propolis

Contact Info

Product

Resources

About