Ozone in medicine

Michalski, Konrad; Michalska, Małgorzata Majka Kulińska

doi:10.26444/monz/111999

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…An allotropic form of oxygen applied for the disinfection of drinking water and closed spaces (ozonation), and is increasingly frequently used in medicine due to its effect as an anti-viral, anti-fungal, and anti-bacterial agent. Due to this effect, ozone therapy is applied, among others, in dentistry, dermatology, orthopaedics, surgery, gyneacology, and opthalmology [64]. The wide therapeutic use of ozone in dentistry is due to its properties: antimicrobial, stimulating the immune system, analgesic, detoxifying, anti-hypoxic, biosynthetic and biostimulant.…”

Section: Polyphenols Possess a Tremendous Antioxidation Potentialmentioning

confidence: 99%

Effect of oxidants and antioxidants on oral health

Dąbrowska¹,

Bijowski²,

Dąbrowska³

et al. 2020

Med Og Nauk Zdr.

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Introduction. Oxidation-reduction processes are an element of the majority of biological processes. An excess of free radicals (FR) and reactive oxygen species (ROS) leading to the development of oxidative stress are the cause of many general and local diseases, such as: diabetes, rheumatiod arthritis, atherosclerosis, periodontal diseases and diseases of other elements of the masticatory organ. The sources of free radical to which the oral cavity is exposed are the air, water, food, stimulants, drugs, and other xenobiotics. Constant exposure to FR has led to the development in the oral cavity of antioxidative defence mechanisms. Simultaneously, the provision to the oral cavity environment of anti-oxidants, such as: vitamins C and E, carotenoids, flavonoids, reduces oxidative stress in the oral cavity environment. Objective. The aim of the study is presentation of the current state of knowledge concerning the effect of oxidants and anti-oxidants on the oral cavity environment. Materials and method. Based on scientific literature in the past few years, the results of studies concerning oxidationreduction processes in the oral cavity environment were analyzed, and endogenous and exogenous factors for oxidation, as well as anti-oxidation discussed. Etiologic factors of the pathogenic processes were indicated in the course of oxidative stress, and the possibilities of its reduction due to antioxidants. Conclusions. Oxidative stress as an etiologic factor of pathological processes in the oral cavity may be balanced or weakened as a result of the action of antioxidation mechanisms of endogenous origin (salivary protective components), and exogenous contained in food and medicinal products. This creates the possibility for development of prophylactic programmes in oral diseases.

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Section: Polyphenols Possess a Tremendous Antioxidation Potentialmentioning

confidence: 99%

Effect of oxidants and antioxidants on oral health

Dąbrowska¹,

Bijowski²,

Dąbrowska³

et al. 2020

Med Og Nauk Zdr.

View full text Add to dashboard Cite

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Local Ozone Therapy in Complex Treatment of Venous Leg Ulcers: Ozone therapy for venous leg ulcers

Pasek

Szajkowski

Cieślar

2022

The International Journal of Lower Extremity Wounds

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A significant health problem in many countries of the world is the occurrence of hard to heal leg ulcers. In recent years modern methods of physical medicine in comprehensive treatment have been used often including ozone therapy. The study included 54 patients, 25 male and 29 female in age between 39 and 87 years (mean age: 66.7 ± 11.9 years) with venous leg ulcers who underwent a cycle of local ozone therapy. The progress in wound healing was evaluated by computerized planimetry and pain intensity was assessed with use a visual analog scale (VAS) . As a result of the applied local ozone therapy a statistically significant reduction of the ulcer area was achieved from median 7.1 (5.6-9.4) cm2 to 4.4 (3-7) cm2 ( P = .000001), which was on median 38.74 (27.27-51.42)% compared to the baseline values before the start of the therapy. In 2 patients (3.7%) the ulcers were completely healed. 18 patients (33.3%) achieved a reduction in ulcer area of more than 50% of the baseline value and the remaining 34 patients (63%) also achieved a reduction in ulcer area. A statistically significant in the percentage of surface area was observed in the group of 19 patients suffering from > 5 years of age compared to the group of 35 patients suffering from ≤5 years (median 50 (32.03-67.16)% versus 33.96 (23.71-45); P = .033178), while percentage changes in ulcer surface area did not differ significantly between all other subgroups of patients. There was also a statistically significant reduction in the intensity of pain in VAS scale in all patients, median 6 (5-7) points before treatment versus 4.4 (3-7) points after treatment, P = .000001). Local ozone therapy of venous leg ulcers accelerate the healing process of ulcers in objective planimetric assessment and reduce the intensity of pain ailments.

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Ozone in medicine

Cited by 2 publications

References 9 publications

Effect of oxidants and antioxidants on oral health

Effect of oxidants and antioxidants on oral health

Local Ozone Therapy in Complex Treatment of Venous Leg Ulcers: Ozone therapy for venous leg ulcers

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