Introduction. Oxidation-reduction processes are an element of the majority of biological processes. An excess of free radicals (FR) and reactive oxygen species (ROS) leading to the development of oxidative stress are the cause of many general and local diseases, such as: diabetes, rheumatiod arthritis, atherosclerosis, periodontal diseases and diseases of other elements of the masticatory organ. The sources of free radical to which the oral cavity is exposed are the air, water, food, stimulants, drugs, and other xenobiotics. Constant exposure to FR has led to the development in the oral cavity of antioxidative defence mechanisms. Simultaneously, the provision to the oral cavity environment of anti-oxidants, such as: vitamins C and E, carotenoids, flavonoids, reduces oxidative stress in the oral cavity environment. Objective. The aim of the study is presentation of the current state of knowledge concerning the effect of oxidants and anti-oxidants on the oral cavity environment. Materials and method. Based on scientific literature in the past few years, the results of studies concerning oxidationreduction processes in the oral cavity environment were analyzed, and endogenous and exogenous factors for oxidation, as well as anti-oxidation discussed. Etiologic factors of the pathogenic processes were indicated in the course of oxidative stress, and the possibilities of its reduction due to antioxidants. Conclusions. Oxidative stress as an etiologic factor of pathological processes in the oral cavity may be balanced or weakened as a result of the action of antioxidation mechanisms of endogenous origin (salivary protective components), and exogenous contained in food and medicinal products. This creates the possibility for development of prophylactic programmes in oral diseases.
Cadmium (Cd) is one of the most harmful xenobiotics to which humans are exposed, mainly by the oral route, throughout life. Preventive strategies are searched as low intoxication with this element, among others due to its prooxidative properties, can be deleterious to health and the exposure to it is continuously increasing. Recently, interest has been paid to plant raw materials with a high antioxidative potential to oppose the prooxidative properties of cadmium, such as black chokeberry (Aronia melanocarpa L. fruit), which is rich in polyphenolic compounds. The study was aimed at assessing whether the chokeberry extract may counteract the prooxidative impact of low-level and moderate repeated intoxication with cadmium on the sublingual salivary gland. The investigation was performed on 96 Wistar rats (females), which were treated with a 0.1% aqueous extract from chokeberries or/and a diet containing 1 or 5 mg Cd/kg for 3 and 10 months, and control animals. The intoxication with cadmium, in a dose- and time-dependent manner, attenuated the enzymatic and nonenzymatic antioxidative potential and increased the concentration of hydrogen peroxide and total oxidative status of the sublingual salivary gland resulting in an occurrence of oxidative stress, enhancement of lipid peroxidation, and oxidative injuries of proteins in this salivary gland. The treatment with the black chokeberry extract during the intoxication with cadmium prevented this xenobiotic-caused oxidative/reductive imbalance and oxidative modifications of proteins and lipids in the salivary gland. The above results allow the conclusion that the consumption of black chokeberry products during intoxication with cadmium can prevent oxidative stress and its consequences in the sublingual salivary gland and thus counteract the unfavourable impact of this xenobiotic on the oral cavity.
Introduction. Demographic forecasts for the Polish population indicate that in 2030 in Poland, that the elderly will constitute approximately 24% of the population. Functional dentition and providing physiological and social benefis are part of the physical and mental well-being of an elderly patient with missing dentition and general diseases. Objective. The aim of the study is to discusses the most common ailments encountered in geriatric patients treated by dentists. Etiology, characteristics and treatment options for the described ailments are taken into account. In dental treated patients age over 60, the most common problems encountered are: stomatopathies, xerostomia and burning mouth syndrome (BMS). Stomatopathies werethe most common in diabetic patients, and in patients using removable or fixed prosthetic restorations. Materials and method. Analysis of the assumed aims of the paper was carried out based on the available literature. Particular attention was paid to the most common complaints in elderly patients. Conclusions. All the above-listed oral cavity health conditions affect the well-being, i.e. physical and mental health of a patient. Local pathological states, such as prosthetic stomatopathies, pass mainly by eliminating the cause of contact inflammation. Other ailments: periodontitis, BMS or xerostomia, are closely related to the general condition of the patient. Changes in the oral cavity depend on the intensity and stabilization of the general disease. His is the reason that a very important role is played by the attending physicians: diabetologists, neurologists or psychiatrists. The cooperation of a dentist with a general practitioner can significantly improve the health of geriatric patients.
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