Oxytocin versus no treatment or delayed treatment for slow progress in the first stage of spontaneous labour

Abstract

For women making slow progress in spontaneous labour, treatment with oxytocin as compared with no treatment or delayed oxytocin treatment did not result in any discernable difference in the number of caesarean sections performed. In addition there were no detectable adverse effects for mother or baby. The use of oxytocin was associated with a reduction in the time to delivery of approximately two hours which might be important to some women. However, if the primary goal of this treatment is to reduce caesarean section rates, then doctors and midwives may have to look for alternative options.

Judicious use of oxytocin augmentation for the management of prolonged labor

“…Previous studies have documented that oxytocin augmentation is associated with a shorter duration of labor, which is in accordance with our findings . Childbirth satisfaction is an important health outcome and it may be desirable to avoid long labors .…”

Judicious use of oxytocin augmentation for the management of prolonged labor

“…Previous studies have documented that oxytocin augmentation is associated with a shorter duration of labor, which is in accordance with our findings . Childbirth satisfaction is an important health outcome and it may be desirable to avoid long labors .…”

Outcomes of Nulliparous Women With Spontaneous Labor Onset Admitted to Hospitals in Preactive Versus Active Labor

“…33 While studies comparing oxytocin use to no treatment are sparse, authors of a recent Cochrane review reported that early versus delayed oxytocin use resulted in a higher risk of uterine tachysystole associated with fetal heart rate changes requiring intervention (risk ratio [RR], 2.51; 95% CI, 1.04-6.05). 34 This is consistent with our findings that two-thirds of the women who had cesareans performed for nonreassuring fetal status had exogenous oxytocin augmentation. Oxytocin use is not proven to decrease the number of woman having cesareans, the role for which it is primarily used (RR, 0.88; 95% CI, 0.66-1.19), although early oxytocin use is reported to reduce the mean duration of labor by approximately 2 hours.…”

Clinical experiences with the use of oxytocin injection by healthcare providers in a southwestern state of Nigeria: A cross-sectional study

“…The pattern of indications for oxytocin use is similar to the Nepal study in which the majority (78%) of health service providers used oxytocin for prevention and management of PPH, while 59 percent used oxytocin for augmentation and induction of labor [19]. Our study is consistent with previous studies that oxytocin may be very commonly and inappropriately used for induction and augmentation of labor [20,23], evident that a significant proportion (80%) almost routinely use oxytocin in augmentation of labor [5,24,25].…”

Judicious use of oxytocin augmentation for the management of prolonged labor

“…Previous studies have documented that oxytocin augmentation is associated with a shorter duration of labor, which is in accordance with our findings . Childbirth satisfaction is an important health outcome and it may be desirable to avoid long labors .…”

Outcomes of Nulliparous Women With Spontaneous Labor Onset Admitted to Hospitals in Preactive Versus Active Labor

“…33 While studies comparing oxytocin use to no treatment are sparse, authors of a recent Cochrane review reported that early versus delayed oxytocin use resulted in a higher risk of uterine tachysystole associated with fetal heart rate changes requiring intervention (risk ratio [RR], 2.51; 95% CI, 1.04-6.05). 34 This is consistent with our findings that two-thirds of the women who had cesareans performed for nonreassuring fetal status had exogenous oxytocin augmentation. Oxytocin use is not proven to decrease the number of woman having cesareans, the role for which it is primarily used (RR, 0.88; 95% CI, 0.66-1.19), although early oxytocin use is reported to reduce the mean duration of labor by approximately 2 hours.…”

Clinical experiences with the use of oxytocin injection by healthcare providers in a southwestern state of Nigeria: A cross-sectional study

“…The pattern of indications for oxytocin use is similar to the Nepal study in which the majority (78%) of health service providers used oxytocin for prevention and management of PPH, while 59 percent used oxytocin for augmentation and induction of labor [19]. Our study is consistent with previous studies that oxytocin may be very commonly and inappropriately used for induction and augmentation of labor [20,23], evident that a significant proportion (80%) almost routinely use oxytocin in augmentation of labor [5,24,25].…”

Judicious use of oxytocin augmentation for the management of prolonged labor

“…Previous studies have documented that oxytocin augmentation is associated with a shorter duration of labor, which is in accordance with our findings . Childbirth satisfaction is an important health outcome and it may be desirable to avoid long labors .…”

Outcomes of Nulliparous Women With Spontaneous Labor Onset Admitted to Hospitals in Preactive Versus Active Labor

“…33 While studies comparing oxytocin use to no treatment are sparse, authors of a recent Cochrane review reported that early versus delayed oxytocin use resulted in a higher risk of uterine tachysystole associated with fetal heart rate changes requiring intervention (risk ratio [RR], 2.51; 95% CI, 1.04-6.05). 34 This is consistent with our findings that two-thirds of the women who had cesareans performed for nonreassuring fetal status had exogenous oxytocin augmentation. Oxytocin use is not proven to decrease the number of woman having cesareans, the role for which it is primarily used (RR, 0.88; 95% CI, 0.66-1.19), although early oxytocin use is reported to reduce the mean duration of labor by approximately 2 hours.…”

Clinical experiences with the use of oxytocin injection by healthcare providers in a southwestern state of Nigeria: A cross-sectional study

“…The pattern of indications for oxytocin use is similar to the Nepal study in which the majority (78%) of health service providers used oxytocin for prevention and management of PPH, while 59 percent used oxytocin for augmentation and induction of labor [19]. Our study is consistent with previous studies that oxytocin may be very commonly and inappropriately used for induction and augmentation of labor [20,23], evident that a significant proportion (80%) almost routinely use oxytocin in augmentation of labor [5,24,25].…”