Oxidative stress in the kidney of reproductive male rats during aging

Alabarse, Paulo Vinícius Gil; Salomon, Tiago Boeira; Medeiros, Tássia Machado; Hackenhaar, Fernanda Schäfer; Schüller, Ártur Krumberg; Ehrenbrink, Guilherme; Benfato, Mara da Silveira

doi:10.1016/j.exger.2011.05.006

Cited by 6 publications

(4 citation statements)

References 62 publications

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“…Protein carbonylation was significantly reduced in the older groups when compared to the 6-and 12-month-old groups, similar to data presented by Alabarse et al 20 . This phenomenon may be related to lower oxygen consumption at an older age, due to a decreased total amount of proteins in the tissues, with glomeruli progressively being replaced by fibrous tissue 11 .…”

Section: Discussionsupporting

confidence: 90%

“…Regarding the renal weight changes observed in rats during aging, Takeda and Alabarse et al 20 reported data similar to those of the present study, reinforcing the possibility that the renal weights do not significantly vary during the aging process 20 . However, they reported a mean kidney weight slightly higher than that found in this study.…”

Section: Discussionsupporting

confidence: 90%

“…In contrast to the animals analyzed in this study, Uzun et al 27 found that SOD activities were significantly lower in renal tissues from 24-month-old rats than those from 6-month-old rats. Other previous studies revealed no significant difference in SOD activities in renal tissues during the aging process 20,32 .…”

Section: Discussionmentioning

confidence: 63%

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Stereological study and analysis of oxidative stress during renal aging in rats

et al. 2020

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 90%

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Stereological study and analysis of oxidative stress during renal aging in rats

et al. 2020

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“…The Hip is considered to be the most vulnerable region to changes in normal Hb levels and neurodegenerative diseases [ 19 ]. Normal aging and degenerative processes in the Hip are accompanied by changes in the number and function of neurons and glia, their volumes, and various factors such as neurotransmitters and hormones [ 20 , 21 ]. The Hip is one of the oldest brain regions, phylogenetically.…”

Section: Introductionmentioning

confidence: 99%

Distribution and Morphological Characteristics of Oligodendrocytes in Selected Areas of the Brain of Male and Female Red Kangaroos (Macropus rufus)

et al. 2022

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This study was carried out on six adult red kangaroos of both sexes. To determine the location of the oligodendrocytes (OLGs) of the hippocampus (Hip) and corpus callosum (CC), the method of impregnation of the neuroglia with silver salts was applied. The iron distribution in the OLGs was determined by the histochemical method. The Nissl method was used to determine the location of the brain structure and to analyze the number of OLGs. In the Hip, these cells are located one beside another, mainly in blood vessels and neurons; in the neocortex (NC), they are located in layers I–VI; and in the CC, they are arranged in characteristic rows and accompany both nerve fibers and blood vessels. The analysis of the results obtained by the chosen methods in the Hip, NC, and CC in males and females did not show statistically significant differences in the distribution and location of the red kangaroo OLGs. The involvement of these cells is a physiological process that proceeds in a similar manner throughout the life of individuals and actively influences the metabolism of neurons and myelin.

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Oxidative stress in the kidney of reproductive female rats during aging

et al. 2013

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Reproduction is a costly life process, and the reproductive investment by females appears to be greater than males in many species. We have analyzed the effects of reproductive investment during aging with respect to oxidative stress parameters in female Wistar rats. We measured the activity glutathione peroxidase, glutathione S-transferase, superoxide dismutase, consumption of hydrogen peroxide, protein carbonylation, lipid peroxidation, nitrite and nitrate levels, and Vitamin C (Vit. C) and E levels. We traced oxidative profiles at ages 3, 6, 12, and 24 months. Animals were grouped according to reproductive experience: experienced or naive with respect to reproductive activity. We measured aconitase activity and sex hormone levels. The naive animals exhibited an increase with respect to experienced in most parameters studied at 6 and 24 months, whereas experienced animals exhibited a similar increase at 3 and 12 months. At 6 months of age, during the period that would represent peak reproductive activity, naive animals showed higher levels of MDA, Vit. C, consumption of hydrogen peroxide and GPx, aconitase, and SOD activities. In naive elderly rats, we observed an increase in oxidative damage markers and an increase in enzymatic and non-enzymatic antioxidants, with the exception of consumption of hydrogen peroxide and Vit. C. In the long term, the reproductive investment was not sufficient to interfere with antioxidant capacity, and did not contribute to oxidative damage in kidneys of female Wistar rats.

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Oxidative stress in the kidney of reproductive male rats during aging

Cited by 6 publications

References 62 publications

Stereological study and analysis of oxidative stress during renal aging in rats

Stereological study and analysis of oxidative stress during renal aging in rats

Distribution and Morphological Characteristics of Oligodendrocytes in Selected Areas of the Brain of Male and Female Red Kangaroos (Macropus rufus)

Oxidative stress in the kidney of reproductive female rats during aging

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