Oxidative Capacity of Human Muscle Fiber Types: Effects of Age and Training Status

Proctor, David N.; Sinning, W. E.; Sieck, Gary C.

doi:10.1249/00005768-199505001-00247

Cited by 56 publications

(114 citation statements)

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“…Our results were comparable with those of several cross-sectional studies that demonstrated a reduced number and mean area of type II muscle-fast fibers in untrained [3,4,5,6,7] as well as in endurance-trained subjects [8,13,14]. A plausible explanation could be that reduced resistance training among older subjects could arguably have contributed to the decrease in fast fiber size, although selective involvement of motor neurons, particularly the larger motor neurons innervating type II fibers, cannot be ruled out [20].…”

Section: Discussionsupporting

confidence: 91%

“…So far, most studies have shown that constant endurance training does not delay waste of muscle mass and atrophy of type II fibers associated with the aging process [8,12,13,14]. However, a study conducted by Klitgaard et al 1990 found that muscle fiber size and muscle force characteristics among elderly men with 12–17 years of heavy resistance training were comparable to those of young adult control subjects.…”

Section: Discussionmentioning

confidence: 99%

“…The impact of a long period of physical activity on age-related modifications in skeletal muscle structure has been studied; however, data on gender-related morphological changes are lacking. Loss of type II fibers has been associated with physical inactivity, mainly in men [3,4,5,6,7], which can be prevented by endurance training [8]. An understanding of the extent to which aging and physical activity processes induce muscle fiber loss has not been elucidated.…”

Section: Introductionmentioning

confidence: 99%

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An Age-Related Morphometric Profile of Skeletal Muscle in Healthy Untrained Women

Bougea

Papadimas

Papadopoulos

et al. 2016

JCM

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There is a paucity of data on muscle biopsies in females of mixed ages in terms of age-related changes. Cross sections of autopsy material including the quadriceps femoris and biceps brachii muscles were obtained from 23 healthy women, aged 24–82 years, who had suffered sudden death. We calculated the percentage of the number, and the mean diameter, of type I and type II muscle fibers within the fascicles as well as in their peripheral parts. The number of type II fibers were shown to reduce significantly with age (p < 0.005), especially in the fascicle periphery, but the percentage of type 1 fibers did not alter significantly. It was noted that type II fibers diminished in size with age, indicating a relationship between fiber size and age. This result became more apparent in the fascicle periphery (p < 0.05). In women, type II muscle fibers were seen to reduce in size and number with advancing age. We postulate that regular physical activity can increase the size of type II muscle fibers, thus helping to both prevent and treat age-related muscle loss.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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An Age-Related Morphometric Profile of Skeletal Muscle in Healthy Untrained Women

Bougea

Papadimas

Papadopoulos

et al. 2016

JCM

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“…There is still limited research describing the relationship between (i) ageing, (ii) inactivity and (iii) exercise on microvascular structural changes in skeletal muscle (Proctor et al. 1995, Williamson et al.…”

Section: Parameters Of Skeletal Muscle Capillarization Identified In mentioning

confidence: 99%

“…Previous studies of the elderly have shown minimal to significant reductions in muscle capillarization compared with younger counterparts. However, the cross‐sectional design of many investigations may limit their validity in describing changes because of ageing (Proctor et al. 1995, Trappe et al.…”

Section: Parameters Of Skeletal Muscle Capillarization Identified In mentioning

confidence: 99%

The influence of endurance and resistance exercise on muscle capillarization in the elderly: a review

Harris

2005

Acta Physiologica Scandinavica

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Part of the difficulty in determining the nature of these relationships has been the inconsistency in research conducted regarding age groups and controlling for past and present activity patterns. Further difficulties comparing across studies arise due to the variety of methods and parameters used to sample and analyse muscle tissue. Standardizing methodology will allow future research to yield more consistent results.

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Fatigue of elbow flexor muscles in younger and older adults

et al. 2001

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The aim of this study was to assess differences in the behavior of fatigue‐related measures of neuromuscular function between younger (n = 10; 20–35 years) and older (n = 11; >65 years) healthy adults. Measures reflecting changes in voluntary activation, neuromuscular propagation, metabolite build‐up, and excitation‐contraction coupling processes were taken before, during, and after a sustained maximum elbow‐flexion fatigue task. We found a greater role for a failure in voluntary activation (central fatigue) in about half of the older subjects compared with none of the younger subjects to explain the decrease in force‐generating capacity with sustained activity. In contrast, similar behaviors in measures reflecting changes in peripheral mechanisms were noted for the two age groups. These results point to a potential shift in fatigue mechanisms with age, with a greater contribution of central fatigue in some older adults. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 98–106, 2001

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Oxidative Capacity of Human Muscle Fiber Types: Effects of Age and Training Status

Cited by 56 publications

References 0 publications

An Age-Related Morphometric Profile of Skeletal Muscle in Healthy Untrained Women

An Age-Related Morphometric Profile of Skeletal Muscle in Healthy Untrained Women

The influence of endurance and resistance exercise on muscle capillarization in the elderly: a review

Fatigue of elbow flexor muscles in younger and older adults

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