Oxidation of amides by laccase-generated aminoxyl radicals

Coniglio, Alessandra; Galli, Carlo; Gentili, Patrizia; Vadalà, Raffaella

doi:10.1016/j.molcatb.2007.09.022

Cited by 53 publications

(24 citation statements)

References 45 publications

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“…The oxidation of even some phenolic substrates by laccase can be low as steric factors may hinder their approach to the active site of the enzyme (D'Acunzo et al, 2006). The small aminoxyl radical species generated from HBT by laccase can abstract H-atom from the O-H bond of these substrates and can form the corresponding phenoxyl radical, which in turn reacts with the substrate (Coniglio et al, 2008). …”

Section: Mediator-enhanced Enzymatic Degradationmentioning

confidence: 99%

Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi

Nguyen

Hai

Yang

et al. 2013

Bioresource Technology

112

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Nghiem, L. D. (2013). Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi. Bioresource Technology, 148 (November), 234-241. Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi AbstractThe degradation of 30 trace organic contaminants (TrOC) by a white-rot fungus-augmented membrane bioreactor (MBR) was investigated. The results show that white-rot fungal enzyme (laccase), coupled with a redox mediator (1-hydroxy benzotriazole, HBT), could degrade TrOC that are resistant to bacterial degradation (e.g. diclofenac, triclosan, naproxen and atrazine) but achieved low removal of compounds (e.g. ibuprofen, gemfibrozil and amitriptyline) that are well removed by conventional activated sludge treatment. Overall, the fungus-augmented MBR showed better TrOC removal compared to a system containing conventional activated sludge. The major role of biodegradation in removal by the MBR was noted. Continuous mediator dosing to MBR may potentially enhance its performance, although not as effectively as for mediator-enhanced batch laccase systems. A ToxScreen3 assay revealed no significant increase in the toxicity of the effluent during MBR treatment of the synthetic wastewater comprising TrOC, confirming that no toxic by-products were produced. 2013 Elsevier Ltd. Abstract:The degradation of 30 trace organic contaminants (TrOC) by a white-rot fungus-augmented membrane bioreactor (MBR) was investigated. The results show that white-rot fungal enzyme (laccase), coupled with a redox mediator (1-hydroxy benzotriazol, HBT), could degrade TrOC that are resistant to bacterial degradation (e.g. diclofenac, triclosan, naproxen and atrazine) but achieved low removal of compounds (e.g. ibuprofen, gemifibrozil and amitriptyline) that are well removed by conventional activated sludge treatment. Overall, the fungus-augmented MBR showed better TrOC removal compared to a system containing conventional activated sludge.The major role of biodegradation in removal by the MBR was noted. Continuous mediator dosing to MBR may potentially enhance its performance, although not as effectively as for mediator-enhanced batch laccase systems. A ToxScreen3 assay revealed no significant increase in the toxicity of the effluent during MBR treatment of the synthetic wastewater comprising TrOC, confirming that no toxic by-products were produced.

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Section: Mediator-enhanced Enzymatic Degradationmentioning

confidence: 99%

Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi

Nguyen

Hai

Yang

et al. 2013

Bioresource Technology

112

View full text Add to dashboard Cite

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“…The biotechnological importance of laccases have increased after the discovery that oxidizable reaction substrate range could be further extended in the presence of small readily oxidizable molecules called mediators (Acunzo and Galli 2003;Morozova et al 2007). During the last two decades, laccases have turned out to be most promising enzymes for industrial uses (Couto and Harrera 2006;Xu 2005) having applications in food, pulp and paper, textile, cosmetics industries and in synthetic organic chemistry (Coniglio et al 2008;Mikolasch et al 2002Mikolasch et al , 2007.…”

Section: Laccasesmentioning

confidence: 99%

Ligninolytic Enzymes for Water Depollution, Coal Breakdown, and Paper Industry

Yadav

Singh

Yadava

et al. 2015

Environmental Chemistry for a Sustainable World

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“…However, glucose might not be a suitable substrate for a wastewater treatment process as it might serve as an unwanted growth substrate for microorganisms. Thus, further studies should be focused on the production of combi-CLEAs using other H 2 O 2 -producing enzymes with substrates that are more suitable in the scope of a water treatment process [93].…”

Section: Removal By Lignin-modifying Enzymesmentioning

confidence: 99%

“…The aminoxyl radicals produced from HBT by laccase, due to their small size, can abstract H-atom from the -OH group in the phenolic moiety of the substrates forming the corresponding phenoxyl radicals [95]. These phenoxyl radicals, in turn, react with the substrate via a radical hydrogen atom transfer route [93] that improves the biodegradation potential. The addition of the same redox mediator to the fungal-augmented MBR system described in the previous section, however, did not provide any significant change in the removal efficiency for the three UV filters and TCS [79].…”

Section: Redox Mediator-catalyzed Removalmentioning

confidence: 99%

Fungal-Mediated Biodegradation of Ingredients in Personal Care Products

Díaz-Cruz

Gago-Ferrero

Badia-Fabregat

et al. 2014

The Handbook of Environmental Chemistry

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Many efforts have been devoted in developing technologies to remove emerging organic pollutants from freshwater systems. This chapter examined the applications of the environmental friendly technology based on fungal-mediated treatment for the degradation of ingredients in personal care products (PCPs), which are frequently detected at relevant concentrations in the aquatic environment. PCPs are daily-use products used in large quantity that includes several groups of substances (UV filters, preservatives, fragrances, etc.). Removal efficiencies reported varied significantly among different experimental set-up, organic substance, and type of fungi. The mechanisms and factors governing the degradation of PCPs by fungi, mainly white-rot fungi and their specific lignin-modifying enzymes, are reviewed and discussed. Beyond, the identification of the intermediate products and metabolites produced as well as the degradation pathways available for some PCPs are presented.

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Oxidation of amides by laccase-generated aminoxyl radicals

Cited by 53 publications

References 45 publications

Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi

Removal of trace organic contaminants by an MBR comprising a mixed culture of bacteria and white-rot fungi

Ligninolytic Enzymes for Water Depollution, Coal Breakdown, and Paper Industry

Fungal-Mediated Biodegradation of Ingredients in Personal Care Products

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