“…Studies conducted in vitro have demonstrated that ApoH has the particularity to bind, not only to negatively charged molecules and structures, including anionic phospholipids (PL), but also binds platelets, apoptotic cells (d 'Angeac et al, 2005), mitochondria, DNA as well as bile acids (Schousboe, 1983). Apart from the PL, ApoH also has the ability to bind cellular proteins such as the kidney calmodulin (Rojkjaer et al, 1997), megalin, an endocytic receptor of the renal epithelium (Moestrup et al, 1998), Annexin II (Ma et al, 2000) as well as other binding proteins or receptors including phosphatidylserine PS , LPS (Agar et al, 2011) and TLR2 (Alard et al, 2010).…”