Abstract:The organic extract of the old woman octopus Cistopus indicus (Octopodidae), ubiquitous in the Central and South Indo‐Pacific to the tropical Indian Ocean, was chromatographically fractionated over a reverse‐phase adsorbent to yield two oxygenated spiro heterocyclic compounds, named indiculides A and B. Their structures were elucidated by using comprehensive spectroscopic methods. The radical scavenging potential displayed by indiculide A (IC50 ∼1.2 mM) besides attenuating the cyclooxygenase isoforms (COX‐1/CO… Show more
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