Overview on vitamin D and sunbed use

Pierret, L.; Suppa, Mariano; Gandini, Sara; Marmol, Véronique Del; Gutermuth, Jan

doi:10.1111/jdv.15316

Cited by 10 publications

(7 citation statements)

References 75 publications

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“…Remainder is derived orally from diet or supplements. 4,5 Fish, eggs and milk in the diet are considered good source of D 3 from diet . Vitamin-D 2 (ergocalciferol) is not produced in humans, and is derived from plants.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients

et al. 2020

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Objective: Serum Vitamin-D plays pivotal role in inflammatory and infectious diseases; among them liver infections are more distinct. This study was aimed to determine Vitamin-D status in HCV-infected patients and healthy controls in Faisalabad, Pakistan. Methods: We performed randomized cross-sectional study of 74 individuals from 20th August, 2017 to 20th February 2018 at The University of Faisalabad and Dar us Shifa Clinic, Faisalabad. Fifty-one patients were hepatitis C RNA-PCR positive (22 compensated cirrhotic and 29 decompensated cirrhotic patients). In addition, 23 subjects without liver disease were recruited as healthy control. HCV RNA–PCR was performed by ARTUS ® HCV QS-RGQ V1. Vitamin-D levels were measured by chemiluminescence. SPSS version 20 was used for statistical analysis. Results: The mean level of Vitamin-D was significantly lower in HCV patients in compensated and decompensated cirrhotic patients (26.85 ng/mL & 20.65 ng/mL respectively) as compared to healthy controls (30.41 ng/mL). This study showed sub optimal level of Vitamin-D in 76.5% of HCV patients. Vitamin-D insufficiency (21-29 ng/mL) as prevalent among healthy individuals (47.8%) as well as in HCV patients (39.2%) (P < 0.001). In addition, Vitamin-D levels showed inverse relationship with more severe conditions of liver disease as 55.2% of decompensated cirrhosis patients were sufferer of Vitamin-D deficiency as compared to 13.6% deficiency of Vitamin-D in compensated cirrhotic group (P <0.0001). Conclusion: Suboptimal levels of Vitamin-D (deficiency or insufficiency) are prevalent in patients having hepatitis C infection as compared to healthy controls. Deficiency of Vitamin-D was directly associated with severity of disease. doi: https://doi.org/10.12669/pjms.36.3.1490 How to cite this:Falak S, Aftab L, Saeed M, Islam A. Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients. Pak J Med Sci. 2020;36(3):---------. doi: https://doi.org/10.12669/pjms.36.3.1490 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Introductionmentioning

confidence: 99%

Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients

et al. 2020

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“…It has been demonstrated that this vitamin plays a key role in the maintenance of normal bone mineral density and muscle functions [18], [36]. Moreover, different studies have shown that it may be a mitigation factor for a number of illnesses, including cardiovascular (e.g., hypertension), autoimmune (e.g., multiple sclerosis) and oncologic (e.g., colon cancer) conditions [36], [37]. In the specific case of melanoma, the most serious type of skin cancer, it has been demonstrated that the different forms of vitamin D can have a potential role in reducing DNA damage and increasing DNA repair [38].…”

Section: Resultsmentioning

confidence: 99%

Tanning-Elicited Variations in the Ultraviolet Absorption Spectra of the Cutaneous Tissues: Skin Photobiology and Photomedicine Implications

Baranoski

Alencar

Leeuwen

et al. 2021

2021 43rd Annual International Conference of the IEEE Engineering in Medicine &Amp; Biology Society (EMBC)

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When ultraviolet radiation is absorbed within the cutaneous tissues, it can trigger a number of phenomena that can have detrimental or beneficial consequences to an individual's health. Tanning is among the most visually noticeable of these phenomena. It may result in significant changes in skin pigmentation and thickness. These spectrally-dependent physiological responses, in turn, can elicit variations in the ultraviolet absorption profiles of the cutaneous tissues and, consequently, alter the occurrence of other ultraviolet-induced photobiological processes such as the breaking of DNA strands and the synthesis of previtamin D3. These tanning-elicited variations in the cutaneous tissues' absorption profiles is often tied to the increased presence of melanin throughout these tissues. However, during the tanning, shifts in the relative content of this pigment within certain skin layers can also be observed. In particular, the stratum basale, the innermost epidermal layer where melanogenesis takes place, can have its relative melanin content significantly reduced in comparison with other epidermal layers. Since the aforementioned photobiological phenomena are preferentially brought about within this layer, such pigmentation shifts may have a more pivotal role in skin photobiology than has been assumed to date. Accordingly, in this work, we investigate the impact of spectrally-dependent tanning-elicited physiological responses, with a particular focus on the inter-layer melanin distribution patterns, on the absorption profiles of the main cutaneous tissues. We also examine how variations in these absorption profiles may alter the outcomes of photo-triggered phenomena associated with the onset of different medical conditions. Our findings are expected to contribute to the advance of the current understanding about skin photobiology, which is indispensable for the success of photomedicine initiatives involving this highly complex organ.

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“…It is true that sunbed use can increase the serum levels of 25-OH-D and several studies have confirmed this finding. On the other hand, this increase is in most cases only transient and not sustained if sunbed use is not regular and continuous: a plateau in 25-OH-D level is indeed reached after just a few sunbed sessions due to a balance between photo-production and photo-degradation [23]. There are a number of factors that decrease the skin's production of vitamin D like aging, dark skin, and sunscreen application.…”

Section: Resultsmentioning

confidence: 99%

Van yöresinde D vitamini düzeyleri ile mevsimsel ilişkinin değerlendirilmesi

Çokluk¹,

Balahoroğlu²,

Hakan³

et al. 2019

Acta Medica Alanya

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ÖZAmaç: D vitamini, bazı gıdalarda bulunan ve güneş ışığına maruz kalan öncülerinden sentezlenebilen yağda çözünen bir vitamindir. Serum 25-hidroksi vitamin D (25-OH Vit D) konsantrasyonunun Vitamin D seviyesinin en iyi göstergesi olduğu bilinmektedir. D vitamininin ana kaynağı güneş ışığına maruz kalan ciltten sentez edilmesidir. Çalışmada Van'da hastanemize başvuran hastaların D vitamini düzeylerini geriye yönelik taradık. 25-OH vit D düzeylerinin yaş, cinsiyet ve mevsimsel farklılıkları arasındaki ilişkiyi araştırdık. Gereç ve Yöntem: Yüzüncü Yıl Üniversitesi Tıp Fakültesi Dursun Odabaş TıpMerkezine başvuran 01.01.2013 -01.01.2014 tarihleri arasında 25-OH vit D düzeyleri tespit edilen ve kriterleri sağlayan sonuçlar dahil edildi.Bulgular: Erkeklerin yaş ortalaması (n = 306) 46.65 ± 16.62, kadınlarda (n = 1613) 43.58 ± 15.03 olarak bulundu. Erkeklerde ortalama 25-OH vit D 18.95 ± 7.93 ng / mL ve kadınlarda 14.79 ± 9.42 ng / ml olarak bulundu. Erkeklerin 25-OH D vitamini düzeyleri kadınlardan anlamlı derecede yüksek bulundu (p <0.05). Mevsime göre 25-OH D vitamini seviyeleri analiz edildiğinde, yaz mevsimi için 25-OH Vitamin D ortalaması kış mevsimine ya da Sonbahar-İlkbahar aylarına göre anlamlı olarak yüksekti (p = 0,006).Sonuç: Her ne kadar Van, konumu itibariyle en çok güneş alan şehirler arasında olsa da, tüm mevsimler ve yaş gruplarına göre vitamin D düzeylerinin düşük olduğunu düşünüyoruz. Bu bulgulara göre, Van ilindeki ve çevresindeki vitamin D eksikliğinin düzelmesi için hem beslenme desteğinin hem de D vitamini desteğinin önemli olduğu sonucuna vardık. ABSTRACTAim: Vitamin D is a fat-soluble vitamin which is found in certain foods and can be synthesized from its precursors with exposure of sunlight. It is known that serum 25hydroxy vitamin D (25-OH Vit D) concentration is the best indicator of Vitamin D level. Main source of Vitamin D is the synthesis to the skin with sunlight exposure. In our study we investigated the vitamin D levels of patients administered to our hospital in Van. We aimed to determine any significant difference between age, sex and seasonal differences of the 25-OH vit D levels. Materials and Method:Patients admitted to with 25-OH vit D levels were determined and evaluated respectively. Results:Mean age for males (n=306) was found as 46.65±16.62 and for females (n=1613) as 43.58±15.03. Mean 25-OH vit D in males was found as 18.95±7.93 ng/ mL and in females it was found as 14.79±9.42 ng/ml. 25-OH vit D levels of males were found significantly higher than that of females (p<0.05). When 25-OH vit D levels were analyzed according to season, a mean of 25-OH vit D for the summer season was found significantly higher than those of the winter or autumn-spring months (p=0.006). Although Van receives one of the highest amount of sunlight due to its geographical position, we consider that there exists a deficiency in all age groups in the society, for all seasons. Conclusions: According to these findings we conclude that both nutritional support and Vitamin D supplementation is important for...

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Overview on vitamin D and sunbed use

Cited by 10 publications

References 75 publications

Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients

Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients

Tanning-Elicited Variations in the Ultraviolet Absorption Spectra of the Cutaneous Tissues: Skin Photobiology and Photomedicine Implications

Van yöresinde D vitamini düzeyleri ile mevsimsel ilişkinin değerlendirilmesi

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