Overview of pulmonary tuberculosis and extra pulmonary tuberculosis at the Siloam MRCCC Semanggi cancer hospital in 2018-2020

Abstract

Clinical manifestations and results of investigations using imaging methods for pulmonary and extrapulmonary tuberculosis (TB) are often mistaken for malignancy, so TB is referred to as a "great imitator." This study aims to describe pulmonary TB and extrapulmonary TB patients at the Siloam MRCCC Semanggi Cancer Specialist Hospital in 2018-2020. A retrospective study design was used in the study with a sample of 71 patients according to the inclusion criteria. The research instrument used was the archives of the Anatomical Pathology Laboratory of the Siloam MRCCC Semanggi Cancer Special Hospital in 2018-2020. Pulmonary TB and extrapulmonary TB results were obtained in 2018 14 patients (19.7%), 31 patients (43.6%) in 2019, and 26 patients (36.7%) in 2020. Most TB occurred in the age range of 21-30 years (36.6%) and female sex (67.6%). Based on the location of the lesion, extrapulmonary TB was found in 64 patients (90.1%) and pulmonary TB in 7 patients (9.9%). Clinical diagnosis showed that 12 patients (17%) were suspected of malignancy, and 55 patients (77.4%) were not. After histopathological examination, 43 tuberculous lymphadenites (60.6%), seven bone and joint TB (9.9%), six lung TB (8.5%), four soft tissue TB (5.6%), 4 Genitourinary TB (5.6%), four gastrointestinal & peritoneal TB (5.6%), two cutaneous TB (2.8%), and one central nervous system TB (1.4%). Risk factors play an important role in the occurrence of pulmonary TB and extrapulmonary TB. Histopathological examination is important to exclude the possibility of malignancy in patients with pulmonary TB and extrapulmonary TB so that treatment can be carried out quickly and accurately.

Rifampicin mono resistant tuberculosis (RR-TB): a case report

“…TB is one of the oldest human disease which causes major mortality as more than two million people die due to this disease (Smith, 2003). Indonesia has been ranked as third country with the most frequent of TB infection worldwide, as it counts 8% of TB cases (Marliana Nurprilinda et al, 2023).…”

“…However this disease also affecting other systems, include the respiratory system, presented in the form of parenchymal or extraparenchymal disease as the primary cause of respiratory failure (Chopra et al, 2021). Other system may infected due to hematogenous and lymphogenous spread (Marliana Nurprilinda et al, 2023), such as gastrointestinal (GI) system in the form of abdominal tuberculosis (Putranto et al, 2018), lymphoreticular system (Putranto et al, 2018), skin (Nguyen et al, 2023), central nervous system (CNS) (Rock et al, 2008), musculoskeletal system (Chowdhury and Chakraborty, 2017), reproductive system (Kumar, 2008), and liver (Hickey et al, 2015).…”