Overview of potential individual phenolic compounds of African walnut extracts and cytotoxicity assessment in lung cancer cell line (A549)

Nkwonta, C.G.; Alamar, M. Carmen; Cellek, Selim; Terry, Leon A.

doi:10.17660/actahortic.2021.1329.8

Cited by 2 publications

(10 citation statements)

References 27 publications

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“…Apart from the nuts kernel, the root, bark, and vegetative parts of African walnut are also utilized in ethnobotanical medicine to treat various health conditions. Some of these conditions include malaria, eczema, indigestion, constipation, and diarrhea as well as manage chronic diseases such as diabetes, high blood pressure and cancers (Payal et al, 2015;Suara et al, 2016;Nkwonta et al, 2021). For African breadfruit, the leaves and the bark are mixed in decoctions to treat various diseases including high blood pressure, diabetes, cough, oral thrush, helminthic infection, and gastro-intestinal complications, e.g., constipation (Oyelola et al, 2007;Kuete et al, 2008;Eleazu et al, 2017Eleazu et al, , 2018.…”

Section: Factors Affecting Wider Production and Utilization Of Africa...mentioning

confidence: 99%

“…In addition to macro and micronutrients, pigeon pea also contains many phenolic compounds, such as, flavonoids and stilbenes, that are protective to human health, via their antioxidant and anti-carcinogenic properties and modulating of the gut microbiota (Nix et al, 2015;Talari and Shakappa, 2018;Abebe, 2022). Pigeon peas contain on average about 27 flavonoids, e.g., apigenin, orientin and vitexin (leaves), isoquercitin (pods), and genistein and cajanol (stem and root) (Nix et al, 2015). Pigeon pea leaves show the highest polyphenolic content, compared with pods, stems and roots (Nix et al, 2015), and the white-seeded varieties reportedly contain about a third of the amount in red-seeded varieties (Abebe, 2022).…”

Section: Nutrition Composition and Potential To Contribute To Nutriti...mentioning

confidence: 99%

“…Pigeon peas contain on average about 27 flavonoids, e.g., apigenin, orientin and vitexin (leaves), isoquercitin (pods), and genistein and cajanol (stem and root) (Nix et al, 2015). Pigeon pea leaves show the highest polyphenolic content, compared with pods, stems and roots (Nix et al, 2015), and the white-seeded varieties reportedly contain about a third of the amount in red-seeded varieties (Abebe, 2022). The high phenolic content, in addition to the unique nutritional profile of pigeon pea, could explain why pigeon pea leaf, stem root extracts, as well as seeds, have been found to have cholesterol-lowering and has traditionally been used to manage various conditions, such, diabetes and hepatitis (Kumar et al, 2021;Wei et al, 2022).…”

Section: Nutrition Composition and Potential To Contribute To Nutriti...mentioning

confidence: 99%

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New Challenges and Future Perspectives in Nutrition and Sustainable Diets in Africa

2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Section: Factors Affecting Wider Production and Utilization Of Africa...mentioning

confidence: 99%

Section: Nutrition Composition and Potential To Contribute To Nutriti...mentioning

confidence: 99%

Section: Nutrition Composition and Potential To Contribute To Nutriti...mentioning

confidence: 99%

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New Challenges and Future Perspectives in Nutrition and Sustainable Diets in Africa

2024

Frontiers Research Topics

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“…The fruit pods at early maturity are light greenish in colour while at late maturity, the colour turns to brownish black (Fasina and Ajibola, 1989;Nkwonta et al, 2016). Agro geography of the nut shows that it is grown in the coastal and lowland humid regions of Nigeria between 4° 15′ and 8° N of the equator (Asaolu, 2009;Nkwonta et al, 2021). The nuts are primarily consumed as snacks after processing by boiling or roasting (Nkwonta et al, 2013).…”

Section: Origin and Utilizationmentioning

confidence: 99%

“…This is because African walnut flour is one of the oilseeds that contain all the essential amino acids necessary for various biochemical activities in man, particularly in protein synthesis (Tchiegang et al, 2001;Asaolu, 2009). The high concentrations of Vitamins C and E (Ayoola et al, 2011) as well as the presence of phytochemicals, including polyphenols belonging mainly to the classes of flavonoids and phenolic acids (Nkwonta et al, 2021) in the nut, effects antimicrobial and antioxidation on the products and in consumers.…”

Section: Nutritional Composition and Potential To Improve Nutrition A...mentioning

confidence: 99%

Underutilised food crops for improving food security and nutrition health in Nigeria and Uganda—a review

Nkwonta

Auma

Gong

2023

Front. Sustain. Food Syst.

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Food and nutrition insecurity are pressing global issues, pertinent to the United Nations’ Sustainable Development Goal 2 (zero hunger). About 1 in 10 people globally are food insecure, with both the COVID-19 pandemic and the Ukraine-Russia crisis exacerbating the problem, partly due to unprecedented shortages in major food commodities, such as wheat, rice, and sunflower oil. Food and nutrition security have been negatively impacted in sub-Saharan African countries like Nigeria and Uganda where, prior to both crises, 25% of the population were already food insecure and children under five and women of reproductive age faced severe undernutrition, micronutrient deficiencies, and their associated health challenges. The recent crises have highlighted the need for a paradigm shift from relying on a few crops to a diversified, sustainable food system that harnesses the potential of neglected and underutilized species (NUS) for food and nutrition insecurity solution, especially in low and middle-income countries. Despite their abundance (>100 edible species) and high nutritional value, various political, socio-cultural, and infrastructural factors have deterred commercialization and utilization of NUS in sub-Saharan Africa. Moreover, there are limited sophisticated studies on many of NUS local to the region. This review aimed to discuss selected NUS, peculiar to Nigeria, namely, African walnut (Tetracarpidium conophorium), African breadfruit (Treculia africana), and Uganda, namely, sesame (Sesamus indicum L.) and pigeon pea (Cajanus cajan L.), and their potential to sustainably contribute towards improved food and nutrition security. The crops are briefly described, and their indigenous uses, nutritional value and medicinal properties highlighted. Issues relating to their production, processing, consumption, and exportation are reviewed considering their contribution towards sustainable food systems.

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Overview of potential individual phenolic compounds of African walnut extracts and cytotoxicity assessment in lung cancer cell line (A549)

Cited by 2 publications

References 27 publications

New Challenges and Future Perspectives in Nutrition and Sustainable Diets in Africa

New Challenges and Future Perspectives in Nutrition and Sustainable Diets in Africa

Underutilised food crops for improving food security and nutrition health in Nigeria and Uganda—a review

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