Overview of nebuliser treatment

The Respimat® Development Story: Patient-Centered Innovation

“…1) [6][7][8][9][10][11][12][13][14][15][16]. Recognition of the devastating impact of chlorofluorocarbon (CFC) propellants on the ozone layer led to the adoption of the Montreal Protocol by the United Nations in 1987, which imposed a gradual phasing out of the use of ozone-depleting chemicals [17].…”

“…The HFA pMDIs were Fig. 1 Historical development of inhaler devices [6][7][8][9][10][11][12][13][14][15][16]. CFC chlorofluorocarbon, DPI dry powder inhaler, HFA hydrofluoroalkane, pMDI pressurized metered dose inhaler reformulated to improve drug delivery compared with their CFC counterparts: the introduction of solution aerosols and the use of co-solvents (such as ethanol) resulted in smaller particle sizes and lower plume velocity, thus helping to increase drug deposition in the airways [3,18].…”

Inhaled Therapy in Children

“…Noninvazif olması, kısa etkili bronkodilatörlerde hızlı etkinin başlamasını sağlaması, inhaler antibiyotik kullanımında daha düşük dozlarda etkili olması, inhale kortikosteroid kullanımında oral veya parenteral yolla aynı etkiyi yapması ve enjeksiyona bağlı ağrıya yol açmaması inhaler ilaç kullanımının avantajlarıdır. [2][3][4][5] İn-halasyon tedavisinde amaç, ilaç partiküllerinin akciğer periferine kadar iletilmesidir. Tedavinin etkinliği akciğerlere giren ilaç miktarına ve dağılımına bağlıdır.…”

Effect of Ambient Temperature Variations on Particle Dimesions in Ultrasonic Nebulizers during Cold Vaporization

“…For a relaxed and comfortable life relative humidity is desirable in the range of %30 to %65 in the environment [3]. Humidity in the environment is fundamental for the human health, convenience and comfort [4]. The drugs that used in medicine for diagnosis and therapy must be inhaled with both cold and hot water vapor steam in the patient's body [5].…”