Overlapping neural circuits for visual attention and eye movements in the human cerebellum

Striemer, Christopher L.; Chouinard, Philippe A.; Goodale, Melvyn A.; Ribaupierre, Sandrine de

doi:10.1016/j.neuropsychologia.2015.01.024

Cited by 38 publications

(44 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results further highlight the importance of cerebellar network FC in relation to attention problems, and are in line with recent works that have shown that attention relies on a multitude of regions not traditionally ascribed to the canonical attention networks (Rohr, et al, 2018;Rosenberg, et al, 2016). Indeed, in recent years there has been a surge in studies showcasing the cerebellum's role in attention (Baumann and Mattingley, 2014;Kellermann, et al, 2012;Striemer, et al, 2015). Genetic, animal model, post-mortem and neuroimaging studies, have all reported cerebellar differences between individuals with ADHD and those who are TD (Arime, et al, 2011;Baroni and Castellanos, 2015;Bonvicini, et al, 2016;Chess and Green, 2008;Rubia, et al, 2014;van der Meer, et al, 2016), as well as between TD individuals and those with ASD (for reviews see (Becker and Stoodley, 2013;Crippa, et al, 2016;Stoodley, 2016;Wang, et al, 2014).…”

Section: Discussionsupporting

confidence: 91%

“…A growing body of literature suggests that in addition to cortico-cortico interactions (Corbetta and Shulman, 2002;Fox, et al, 2006;Rohr, et al, 2017), cortico-cerebellar connectivity may play an important role in attention (Baumann and Mattingley, 2014;Kellermann, et al, 2012;Striemer, et al, 2015). Historically, the human cerebellum has been primarily associated with sensorimotor functions (Heck and Sultan, 2002;Marr, 1969), however, evidence has accumulated regarding its role in working memory, executive functioning, language, emotion and social cognition (Schmahmann, 2010;Stoodley and Schmahmann, 2009;Strick, et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Girls’ attentive traits associate with cerebellar to dorsal attention and default mode network connectivity

Rohr

Dimond

Schuetze

et al. 2018

Preprint

View full text Add to dashboard Cite

Attention traits are a cornerstone to the healthy development of children's performance in the classroom, their interactions with peers, and in predicting future success and problems. The cerebellum is increasingly appreciated as a region involved in complex cognition and behavior, and moreover makes important connections to key brain networks known to support attention: the dorsal attention and default mode networks (DAN; DMN). The cerebellum has also been implicated in childhood disorders affecting attention, namely autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), suggesting that attention networks extending to the cerebellum may be important to consider in relation to attentive traits. Yet, direct investigations into the association between cerebellar FC and attentive traits are lacking. Therefore, in this study we examined attentive traits, assessed using parent reports of ADHD and ASD symptoms, in a community sample of 52 girls aged 4-7 years, i.e. around the time of school entry, and their association with cerebellar connections with the DAN and DMN.We found that cortico-cerebellar functional connectivity (FC) jointly and differentially correlated with attentive traits, through a combination of weaker and stronger FC across anterior and posterior DAN and DMN nodes. These findings suggest that corticocerebellar integration may play an important role in the manifestation of attentive traits.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Girls’ attentive traits associate with cerebellar to dorsal attention and default mode network connectivity

Rohr

Dimond

Schuetze

et al. 2018

Preprint

View full text Add to dashboard Cite

show abstract

“…The attentional deficits from cerebellar lesions were most apparent after damage to the left cerebellum. This is consistent with our previous fMRI study (Striemer, Chouinard, et al, 2015) demonstrating significant BOLD activity in the left cerebellum during covert attention tasks, and with the fact that regions of the left cerebellum such as lobule VI, VIII and Crus II are functionally connected to the ventral attention network in the right hemisphere (Buckner et al, 2011;Wang et al, 2013).…”

Section: Discussionsupporting

confidence: 93%

“…Specifically, for reflexive orienting of spatial attention we demonstrated clear evidence that cerebellar damage results in the absence of IOR ( Figure 3A&B). Since voluntary covert attention was unaffected by cerebellar damage, we provide a clear support for our earlier hypothesis that the cerebellum plays a larger role in reflexive than voluntary covert attention (Striemer, Cantelmi, et al, 2015;Striemer, Chouinard, et al, 2015).…”

Section: Discussionsupporting

confidence: 86%

Cerebellar lesions disrupt spatial and temporal visual attention

Craig

Morrill

Anderson

et al. 2019

Preprint

View full text Add to dashboard Cite

2 Cerebellar contributions to spatial and non-spatial attention ABSTRACTThe current study represents the first comprehensive examination of spatial, temporal and sustained attention following cerebellar damage. Results indicated that, compared to controls, cerebellar damage eliminated the onset of inhibition of return (IOR) during the reflexive covert attention task, and reduced the ability to detect successive targets during an attentional blink task.However, cerebellar damage had no effect on voluntary covert attention or the sustained attention to response task (SART). Lesion overlay analysis indicated that impaired performance on IOR and the attentional blink were associated with damage to Crus II and lobule VII (tuber) and VIII (pyramis) of the left posterior cerebellum. Critically, subsequent analyses indicated our results are not due to either general motor impairments or to damage to the deep cerebellar nuclei. Collectively these data demonstrate, for the first time, that the same cerebellar regions are involved in both spatial and temporal visual attention. Furthermore, these data suggest that damage to the cerebellum may induce a form of "attentional dysmetria," such that performance suffers under conditions in which the rapid deployment of attention (either spatial or temporal) is required.

show abstract

“…In addition, the cerebellum also regulates cognition 28,29. The cerebellum has been shown to be involved in the execution of accurate eye movement 30. Moreover, dysfunction of the cerebellum has been shown in many diseases such as autism,31 schizophrenia,32 and ataxia 33.…”

Section: Discussionmentioning

confidence: 99%

Altered spontaneous brain activity pattern in patients with late monocular blindness in middle-age using amplitude of low-frequency fluctuation: a resting-state functional MRI study

Li¹,

Huang²,

Ye³

et al. 2016

CIA

View full text Add to dashboard Cite

ObjectivePrevious reports have demonstrated significant brain activity changes in bilateral blindness, whereas brain activity changes in late monocular blindness (MB) at rest are not well studied. Our study aimed to investigate spontaneous brain activity in patients with late middle-aged MB using the amplitude of low-frequency fluctuation (ALFF) method and their relationship with clinical features.MethodsA total of 32 patients with MB (25 males and 7 females) and 32 healthy control (HC) subjects (25 males and 7 females), similar in age, sex, and education, were recruited for the study. All subjects were performed with resting-state functional magnetic resonance imaging scanning. The ALFF method was applied to evaluate spontaneous brain activity. The relationships between the ALFF signal values in different brain regions and clinical features in MB patients were investigated using correlation analysis.ResultsCompared with HCs, the MB patients had marked lower ALFF values in the left cerebellum anterior lobe, right parahippocampal gyrus, right cuneus, left precentral gyrus, and left paracentral lobule, but higher ALFF values in the right middle frontal gyrus, left middle frontal gyrus, and left supramarginal gyrus. However, there was no linear correlation between the mean ALFF signal values in brain regions and clinical manifestations in MB patients.ConclusionThere were abnormal spontaneous activities in many brain regions including vision and vision-related regions, which might indicate the neuropathologic mechanisms of vision loss in the MB patients. Meanwhile, these brain activity changes might be used as a useful clinical indicator for MB.

show abstract

Overlapping neural circuits for visual attention and eye movements in the human cerebellum

Cited by 38 publications

References 58 publications

Girls’ attentive traits associate with cerebellar to dorsal attention and default mode network connectivity

Girls’ attentive traits associate with cerebellar to dorsal attention and default mode network connectivity

Cerebellar lesions disrupt spatial and temporal visual attention

Altered spontaneous brain activity pattern in patients with late monocular blindness in middle-age using amplitude of low-frequency fluctuation: a resting-state functional MRI study

Contact Info

Product

Resources

About