Overlap of IgA Pemphigus and Linear IgA Dermatosis in a Patient with Ulcerative Colitis: A Mere Coincidence?

IgA/IgG Pemphigus with Infiltration of Neutrophils and Eosinophils in an Ulcerative Colitis Patient

“…In some IgA pemphigus patients, multiple target antigens have been identified (10)(11)(12). Multiple autoantibodies in our patient might be produced via epitope spreading phenomenon.…”

“…A few pemphigus patients were reported to be associated with UC (11,14), and one patient showed IgA autoantibodies to several antigens (11). Mucosal immune response is IgA predominant.…”

Cutaneous implantation of papillary thyroid carcinoma secondary to percutaneous ethanol injection into nodal metastasis

“…6 Distant skin metastases are more common on the scalp and usually herald a bad prognosis (stage IVc). The clinical presentation can be variable, and lesions have been described as patches, plaques, nodules or even mimicking benign and malignant skin neoplasms.…”

“…The clinical presentation can be variable, and lesions have been described as patches, plaques, nodules or even mimicking benign and malignant skin neoplasms. 6 PEI seems to be an effective nonsurgical management option for patients presenting with limited number of lymph node metastases in the neck. Significant responses are detected in more than 80% of cases, and adverse events are apparently uncommon.…”

“…6 Interestingly our patient exhibited the clinical manifestation only of IEN-type IgA pemphigus but in a severe form with an extreme mucosal involvement which is rather rare. Neutrophilic infiltration in the histology and IgA ECS depositions by the direct immunofluorescence were compatible with IgA pemphigus.…”