Overcommitment to Work Is Associated With Changes in Cardiac Sympathetic Regulation

Vrijkotte, Tanja G. M.; Doornen, Lorenz J.P. van; Geus, Eco J. C. de

doi:10.1097/01.psy.0000138283.65547.78

Cited by 58 publications

(53 citation statements)

References 52 publications

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“…Although not uniform , in reaction to work stress, OC has been associated with indicators of sympathetic nervous system activation including elevated blood pressure (Steptoe et al, 2004), shorter pre-ejection period (PEP) levels and reduced PEP variability (Vrijkotte et al, 2004). Moreover, associations between OC and elevated levels of the stress hormone cortisol over the workday have been reported (Eller et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men

Wirtz

Siegrist

Rimmele

et al. 2008

Psychoneuroendocrinology

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Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men Abstract BACKGROUND: Overcommitment (OC) is a pattern of excessive striving. In reaction to work stress, OC has been associated with higher sympathetic nervous system activation and cortisol release, but data on neuroendocrine reactivity to standardized stressors are scarce. We investigated whether OC is associated with differential levels of the stress hormones norepinephrine and cortisol in response to acute psychosocial stress.METHODS: Fifty-eight medication-free non-smoking men aged between 20 and 65 years (mean+/-S.E.M.: 36.3+/-1.8) underwent an acute standardized psychosocial stress task combining public speaking and mental arithmetic in front of an audience. We assessed OC as well as a variety of psychological control variables including vital exhaustion, perfectionism, chronic stress, and cognitive stress appraisal. Moreover, we measured plasma norepinephrine as well as salivary cortisol before and after stress and several times up to 60 min thereafter.RESULTS: Higher OC was associated with lower baseline norepinephrine levels (r = -0.37, p < 0.01). General linear models controlling for age, BMI, and mean arterial blood pressure revealed that higher overcommitment was associated with lower norepinephrine and cortisol levels before and after stress (p's < 0.02) as well as with lower norepinephrine stress reactivity (p = 0.02). Additional controlling for the potential psychological confounders vital exhaustion, perfectionism, chronic stress, and depression confirmed lower norepinephrine levels before and after stress (p < 0.01) as well lower norepinephrine stress reactivity (p = 0.02) with increasing OC. Higher OC independently explained 13% of the total norepinephrine stress response (beta = -0.46, p < 0.01, R(2) change = 0.13).CONCLUSIONS: Our findings suggest blunted increases in norepinephrine following stress with increasing OC potentially mirroring blunted stress reactivity of the sympathetic nervous system. ABSTRACTBackground: Overcommitment is a pattern of excessive striving. In reaction to work stress, overcommitment (OC) has been associated with higher sympathetic nervous system activation and cortisol release, but data on neuroendocrine reactivity to standardized stressors are scarce. We investigated whether overcommitment is associated with differential levels of the stress hormones norepinephrine and cortisol in response to acute psychosocial stress.Methods: 58 medication-free non-smoking men aged between 20 and 65 years (mean±SEM: 36.3±1.8) underwent an acute standardized psychosocial stress task combining public speaking and mental arithmetic in front of an audience. We assessed overcommitment as well as a variety of psychological control variables including vital exhaustion, perfectionism, chronic stress, and cognitive stress appraisa...

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Section: Introductionmentioning

confidence: 99%

Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men

Wirtz

Siegrist

Rimmele

et al. 2008

Psychoneuroendocrinology

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“…After a complete review of the full articles, 87 studies were excluded because they: (i) did not measure the psychosocial work factors of the DCS and/or ERI models (N=39) (39-77), (ii) did not individually assess exposure to psychosocial factors (N=3) (78)(79)(80), (iii) comprised a population of high school students (not a working population) (N=1) (81), (iv) included <100 participants (N=13) (82)(83)(84)(85)(86)(87)(88)(89)(90)(91)(92)(93); (v) were not written in English or French (N=4) (94)(95)(96)(97), (vi) were not published in a peer-reviewed publication (N=16) (11,(98)(99)(100)(101)(102)(103)(104)(105)(106)(107)(108)(109)(110)(111)(112), (vii) did not measure BP (N=8) (70,(113)(114)(115)(116)(117)(118)(119), or (viii) did not distinctly evaluate exposure to psychosocial work factors (N=3) (120)…”

Section: Overview Of Included Studiesmentioning

confidence: 99%

Adverse effects of psychosocial work factors on blood pressure: systematic review of studies on demand–control–support and effort–reward imbalance models

Gilbert-Ouimet¹,

Trudel²,

Brisson³

et al. 2013

Scand J Work Environ Health

180

136

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This is the first systematic review and critical synthesis on the adverse effects of psychosocial work factors of the demand-control-support and effort-reward imbalance models on blood pressure. A more consistent effect has been observed among men than women and among studies of higher methodological quality. Evidence-based guidelines for cardiovascular diseases prevention may benefit from these findings.Affiliation: Population health research unit, St-Sacrement hospital,

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“…Blood pressure, HR, pre-ejection period (PEP; a derivate of sympathetic nervous system activity), 23 and respiratory sinus arrhythmia (RSA; a derivative of parasympathetic nervous system activity) 24 were measured during the health check performed at age 5 to 6 years. 20 To assess PEP and RSA, the VU University-Ambulatory Monitoring System (VU-AMS, Amsterdam, The Netherlands) was used.…”

Section: Blood Pressure Hr Parasympathetic and Sympathetic Activationmentioning

confidence: 99%

Maternal Prepregnancy Body Mass Index and Their Children’s Blood Pressure and Resting Cardiac Autonomic Balance at Age 5 to 6 Years

Gademan

Eijsden²,

Roseboom³

et al. 2013

Hypertension

Self Cite

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Adverse intrauterine conditions can program hypertension. Because one of the underlying mechanisms is thought to be cardiac autonomic balance, we investigated the association between prepregnancy body mass index (BMI) and blood pressure and indicators of the autonomic balance in the child at age 5 to 6 years. Also investigated was whether these associations were mediated by standardized birth weight and child BMI. Pregnant women (n=3074) participating in the Amsterdam Born Children and their Development study completed a questionnaire at gestational week 14. At age 5 to 6 years, offspring’s sympathetic drive (pre-ejection period), parasympathetic drive (respiratory sinus arrhythmia), and heart rate were measured by electrocardiography and impedance cardiography at rest. Blood pressure was assessed simultaneously. After adjusting for possible maternal/offspring confounders, prepregnancy BMI was positively linearly associated with diastolic blood pressure (β=0.11 mm Hg; 95% confidence interval, 0.05–0.17), systolic blood pressure (β=0.14 mm Hg; 95% confidence interval, 0.07–0.21), but not with heart rate, sympathetic or parasympathetic drive. After adding birth weight and child BMI to the model, the independent effect size of prepregnancy body mass index on systolic blood pressure (β=0.07 mm Hg; 95% confidence interval, 0.00–0.14) and diastolic blood pressure (β=0.07 mm Hg; 95% confidence interval, 0.01–0.13) decreased by ≈50%. Birth weight did not mediate these relationships, but was independently and negatively associated with blood pressure. Child BMI was positively associated with blood pressure and partly mediated the association between prepregnancy BMI and blood pressure. In conclusion, higher prepregnancy BMI is associated with higher blood pressure in the child (aged 5–6 years) but does not seem to be attributable to early alterations in resting cardiac autonomic balance. Child BMI, but not birth weight, mediated the association between prepregnancy BMI and blood pressure.

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Overcommitment to Work Is Associated With Changes in Cardiac Sympathetic Regulation

Cited by 58 publications

References 52 publications

Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men

Higher overcommitment to work is associated with lower norepinephrine secretion before and after acute psychosocial stress in men

Adverse effects of psychosocial work factors on blood pressure: systematic review of studies on demand–control–support and effort–reward imbalance models

Maternal Prepregnancy Body Mass Index and Their Children’s Blood Pressure and Resting Cardiac Autonomic Balance at Age 5 to 6 Years

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