“…In a murine model of influenza-associated IPA, baloxavir marboxil, a cap-dependent endonuclease inhibitor, was shown to improve weight loss, survival, viral clearance, and decreased fungal invasion. Baloxavir marboxil-treated mice had higher levels of alveolar macrophages in bronchoalveolar lavage fluid compared to non-treated mice, which could play a role in fungal burden and fungal invasion during IAPA [ 40 ].…”