2004
DOI: 10.1016/j.jneumeth.2004.02.019
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Over-pulsing degrades activated iridium oxide films used for intracortical neural stimulation

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Cited by 189 publications
(153 citation statements)
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“…An electroactive area will measure the total electrochemically functional electrode area including its roughness (regions that are non-or poorly conducting will not be 6 6…”
Section: Resultsmentioning
confidence: 99%
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“…An electroactive area will measure the total electrochemically functional electrode area including its roughness (regions that are non-or poorly conducting will not be 6 6…”
Section: Resultsmentioning
confidence: 99%
“…DBS electrodes are currently all platinum, and the charge density is usually assessed by cyclic voltammetry 5,6 . Under this condition, the charge density is related to the capacitance current generated at the electrode-solution interface.…”
Section: Introductionmentioning
confidence: 99%
“…More recently, a range of new electrode materials and coatings have been proposed: Iridium oxide is a material able to undergo Faradaic electrochemical reactions, resulting in a much larger charge capacity than pure planar or roughened metal electrodes [7] but its long term stability issues, particularly at high current injection levels, limit its potential for chronic implantation [8][9][10][11].…”
Section: Introductionmentioning
confidence: 99%
“…Perceptual threshold measurements obtained in blind humans have varied widely, although 0.5 ÎŒC/phase is reasonably good representation of the collective results [8]. However, charge densities of >2000 ÎŒC/cm 2 can result in substantial damage to the electrode and tissue [9,10]. Thus, large electrodes (>175 ÎŒm diameter) are required to supply the needed charge to minimize charge density and the risk of electrode or tissue damage.…”
Section: Introductionmentioning
confidence: 99%