OVARIAN VENOUS BLOOD Po2, Pco2 AND pH IN WOMEN

Abstract

Measurements of Po2, Pco2 and pH have been carried out in human ovarian venous, peripheral venous and arterial blood, and in ovarian follicular fluid. The Po2 in ovarian venous blood is higher than in peripheral venous blood. Mean oxygen consumption by the human ovary has been calculated to be 1\m=.\4ml oxygen/100 g ovarian tissue/min. Taken in conjunction with a mean ovarian blood flow of 20\m=.\3ml/min, these findings are compatible with the presence of arterio-venous shunts within the human ovary. Oxygen tension in follicular fluid may be substantially lower than oxygen tension in peripheral and ovarian venous blood.

THE PO2, PCO2, pH AND OXYGEN CONTENT OF OVARIAN VENOUS BLOOD OF SHEEP

“…In women the mean ovarian blood flow (calculated by the Fick principle; Baird, 1970) of 20-3±3-3 (s.e.m.) ml/min or 2-3 ml/g/min (Fraser et al 1973) is comparable to that estimated in the ewe in the present study.…”

“…The mean oxygen consumption during the control hour of the LH-infusion experiment of 0-135 ml 02/min or 0-03-0-05 ml/g/min (assuming an ovarian weight of 3-4 g) was similar to that calculated in vivo in women (0-014 ml/ g/min; Fraser et al 1973). Infusion of LH produced a significant increase in ovarian blood flow together with a doubling of oxygen consumption (Fig.…”

“…1). In a similar study conducted in women under anaesthesia the mean difference in P02 between ovarian and peripheral venous blood was 15-5 ±5-4 mmHg (P < 0-005) (Fraser et al 1973). In the absence of any difference in pH, PC02 or haematocrit these findings suggest that the oxygen content of ovarian venous blood is higher than that of jugular venous blood.…”

“…Ovarian venous blood has frequently been noted to be much brighter red than jugular venous blood suggesting that it has a higher oxygen saturation. It has recently been reported that P02 in human ovarian venous blood collected from women at the time of surgery, is significantly higher than that of peripheral venous blood (Fraser, Baird & Cockburn, 1973). These findings would be in keeping with a considerable shunting of blood from the ovarian arterioles to the venous circula¬ tion, bypassing the ovarian capillary network (Mattner & Thorburn, 1969;Goding et al 1972).…”

PALMERSTON NORTH, NEW ZEALAND The effects of IVF aspiration on the temperature, dissolved oxygen levels, and pH of follicular fluid

“…Fluid cannot simply be aspirated into the bulk collection tube and analyzed for oxygen. The large variation (7-17 vol.%) in reported values of dissolved oxygen in follicular fluid (9)(10)(11)(12)(13) suggests that either the populations are different, or that analytical errors are present. Inadequate attention to avoidance of oxygen level changes during fluid sampling may underlie the variation observed in these reports.…”